The bicyclic ketone shown below is first treaterd with a base, then ethyliodide is added to form the substituted ketone. Which base/conditions are suitable?1) Base2)O 1. Lithium disopropylamide in THF at -78 *C.O 2. NABH4 in methanol at room temperature.3. Sodium methoxide in methanol at room temperature.O 4. DBU in THF at 25 "C.

The question is based on the concept of organic reactions. We have to determine which of the given…

Answered: 1) Base 2) O 1. Lithium…

1) Base 2) O 1. Lithium diisopropylamide in THF at -78 "C. O 2 NABH4 in methanol at room temperature. O 3. Sodium methoxide in methanol at room temperature. O 4. DBU in THF at 25 "C.

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter8: Haloalkanes, Halogenation, And Radical Reactions

Section: Chapter Questions

Problem 8.28P

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Concept explainers

Ionic Equilibrium

Chemical equilibrium and ionic equilibrium are two major concepts in chemistry. Ionic equilibrium deals with the equilibrium involved in an ionization process while chemical equilibrium deals with the equilibrium during a chemical change. Ionic equilibrium is established between the ions and unionized species in a system. Understanding the concept of ionic equilibrium is very important to answer the questions related to certain chemical reactions in chemistry.

Arrhenius Acid

Arrhenius acid act as a good electrolyte as it dissociates to its respective ions in the aqueous solutions. Keeping it similar to the general acid properties, Arrhenius acid also neutralizes bases and turns litmus paper into red.

Bronsted Lowry Base In Inorganic Chemistry

Bronsted-Lowry base in inorganic chemistry is any chemical substance that can accept a proton from the other chemical substance it is reacting with.

Question

The bicyclic ketone shown below is first treaterd with a base, then ethyliodide is added to form the substituted ketone. Which base/conditions are suitable?
1) Base
2)
O 1. Lithium disopropylamide in THF at -78 *C.
O 2. NABH4 in methanol at room temperature.
3. Sodium methoxide in methanol at room temperature.
O 4. DBU in THF at 25 "C.

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