1. Arrange the following in the order of decreasing reactivity towards a nucleophile. (Number them 1-5) acid amide acid halide ester 4 carboxylic acid acid anhydride 2. Rationalize the order of reactivity in #1. 3. 2.

1. Arrange the following in the order of decreasing reactivity towards a nucleophile. (Number them 1-5) acid amide acid halide ester 4 carboxylic acid acid anhydride 2. Rationalize the order of reactivity in #1. 3. 2.

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter24: Carboxylic Acids & Derivatives

Section: Chapter Questions

Problem 8CTQ

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Question

Rationalize the order of reactivity in #1

1. Arrange the following in the order of decreasing reactivity towards a nucleophile. (Number them
1-5)
acid amide
1
acid halide
ester
carboxylic acid
2
acid anhydride
2. Rationalize the order of reactivity in #1.
3.
4.

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