1.0 1.0 0.8 0.8 ScPfk 0.6 0.6 ScPfk 0.4 0.4 YIPfk 0.2 0.2 2 4 6 8 P-enolpyruvate (mM) 10 23 20 50 100 10 15 Fructose-2,6-P2 (µM) Relative activity (v V-1) Relative activity (v V-1)

Curren'S Math For Meds: Dosages & Sol
11th Edition
ISBN:9781305143531
Author:CURREN
Publisher:CURREN
Chapter6: Oral Medication Labels And Dosage Calculation
Section: Chapter Questions
Problem 9.4P
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Yarrowia lipolytica(Yl) is a non-conventional yeast that diverged from baker’s yeast, Saccharomyces cerevisiae(Sc), early in evolutionary history. The regulation of glycolytic enzymes in Yl differs from that of Sc. The figures below show how PFK activity is affected by fructose-2,6-bisphosphate and phosphoenolpyruvate. Based on these data, which molecule is the major regulator of PFK activity in each species?

 

 

1.0
1.0
0.8
0.8
ScPfk
0.6
0.6
ScPfk
0.4
0.4
0.2
0.2
2 4
6
8
10
%23
50 100
P-enolpyruvate (mM)
10 15 20
Fructose-2,6-P2 (µM)
Relative activity (v V-1)
Relative activity (v V-1)
Transcribed Image Text:1.0 1.0 0.8 0.8 ScPfk 0.6 0.6 ScPfk 0.4 0.4 0.2 0.2 2 4 6 8 10 %23 50 100 P-enolpyruvate (mM) 10 15 20 Fructose-2,6-P2 (µM) Relative activity (v V-1) Relative activity (v V-1)
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