10. Bryostatin is a cyclic polyketide natural product synthesized biologically by the sessile marine organism Bugula neritina. Bryostatin 1 (below) and its derivatives exhibit potent modulation of protein kinase C (PKC), which results in its wide range of therapeutic indications in cancer, HIV, and Alzheimer's Disease. Но OAc MeO2C OH он 19 26 a. What is the maximum number of O' 20 stereoisomers of this natural product that can exist? "Pr CO,Me Bryostatin 1 b. Point out and name all of the non-hydrocarbon (ie; alkanes and alkenes) functional groups. c. Label all of the alcohols as primary, secondary, or tertiary. d. Label the relevant geometry of all alkenes.
10. Bryostatin is a cyclic polyketide natural product synthesized biologically by the sessile marine organism Bugula neritina. Bryostatin 1 (below) and its derivatives exhibit potent modulation of protein kinase C (PKC), which results in its wide range of therapeutic indications in cancer, HIV, and Alzheimer's Disease. Но OAc MeO2C OH он 19 26 a. What is the maximum number of O' 20 stereoisomers of this natural product that can exist? "Pr CO,Me Bryostatin 1 b. Point out and name all of the non-hydrocarbon (ie; alkanes and alkenes) functional groups. c. Label all of the alcohols as primary, secondary, or tertiary. d. Label the relevant geometry of all alkenes.
Chapter13: Kinetic Methods
Section: Chapter Questions
Problem 4P
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