4-nitrophenol is about 2.8 pka units stronger than phenol, 3,5-dimethyl-4- nitrophenol because of the

Q: methylbenzene with propanoyl chloride and AIICI3 to make `CH2-CH3 H3C

A: The mechanism for the electrophilic substitution of the acyl group of propanoyl chloride and methyl…

Q: Which electrophile is most likely to undergo a 1,2-hydride shift during an electrophilic aromatic…

A: In electrophilic aromatic substitution of benzene in presence of AlCl3. First of all the alkyl…

Q: Select all of the following molecules that are capable of acting as hydrogen bond donors: a.…

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Q: a) Calculate the enantiomeric excess of the styrene epoxide to the nearest %. % b) There are some…

A: Interpretation: To calculate enantiomeric excess and also tell whether the smaller peaks between 4…

Q: Convert neopentane (molecule A) to 4,4-dimethylpentanal (molecle B):

A: On halogenation of A in the presence of sunlight (hv), alkyl halide (C) is prepared.

Q: Classify following solvent as protic or aprotic                CH2Cl2

A: Protic solvents are solvents which contains protons bonded with high electronegative oxygen and…

Q: 1. Spectroscopy for Vanillin and  Vanillyl Alcohol : IR , 1HNMR & 13CNMR

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Q: Following are structural formulas for phenol and cyclohexanol along with the acid dis- sociation…

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Q: F

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Q: 1. Rank the list of benzene substituents below from most deactivating to most activating towards…

A: Aromatic compounds undergo electrophilic substitution reaction as it contains pi-electrons and hence…

Q: 2. Write out a detailed recipe for the preparation of benzalacetophenone. formalism) for the…

A: The reaction of an aromatic aldehyde with an aldehyde or ketone forms chalcones.  Benzalacetophenone…

Q: a) Para, ortho and meta nitrophenol are constitutional isomers of one another that all vary in the…

A: Nitro phenols are the derivative of benzene having formula OHC6H5-X(NO2)x. There are 3 types of…

Q: 2. Strychnine (6) is a notorious poison for both humans and rats. The first synthesis of this…

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Q: Rank the following compounds in order of increasing reactivity (least to most reactive) with respect…

A: The acyl substitution reactivity order is given as :-  Amide < Ester < Acid anhydride <…

Q: 2. Each of the circled hydrogens in the compound shown below could potentially be removed by…

A: Here we have to predict which of the following bases will deprotonate the following indicated acidic…

Q: The 1H NMR spectrum of N,N-dimethylformamide shows three singlets at 2.9, 3.0, and 8.0 ppm. Explain…

A: The protons 1H NMR spectrum is taken to identify the environment of protons (H- atoms). The protons…

Q: 8. Between p-Nitrobenzaldehyde and p- Methylbenzaldehyde, which one will show higher Vco? Explain…

A: Infrared spectroscopy is the spectroscopy that deals with the infrared region of the electromagnetic…

Q: Which acid is stronger, 4-phenylphenol or3-phenylphenol? Why?

A: 3-phenyl phenol is more acidic than 4-phenyl phenol. Due to inductive effect of phenyl ring on…

Q: Please help me draw 9-Methoxy-2-phenethyl-4,4-diphenyl-4H-naphtho[2,3- d][1,3]dioxine,

A: Structure representation gives the arrangement of atoms in space.

Q: Propose a short synthesis f or ONE of the following molecules. You can start with acetylene, and…

A: The answer is given as follows

Q: 8. Between p-Nitrobenzaldehyde and p- Methylbenzaldehyde, which one will show higher Vc-o? Explain…

A: p-Nitro benzaldehyde has nitro (NO2) group in the 4th position and p-methyl benzaldehyde has methyl…

Q: The alkaline hydrolysis of the following compound yields: CH3-C-N(CH₂CH3)2 CH3C00+ NH3 + CH3CH2OH…

A: Among the given questions  1st include saponification which is basically the amount of strong base…

Q: Point out the functional group(s) reponsible for its reactivity or functions. 1. BADGE (bisphenol A…

A: Solution: When oxygen atom is bounded with two methyl or alkyl groups called as ether. If, instead…

Q: How many such interactions are present in cyclopropane? What fraction of the overall 115 kj/mol…

A: In staggered form the dihedral angle between the front C-H bond and the back C-H bond is 600 whereas…

Q: a. Compound X is benzene, Y is acetic anhydride acid. Complete the following scheme and determine Z!…

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Q: 14. Phenols are stronger acids than aliphatic alcohols because of resonance stabilization by the…

A: Aliphatic Alcohols resonance structure :

Q: 4. Write out the steps necessary-to convert the compound on the left into the compound on the right…

A: The questions has been answered.

Q: Explain below statement ? The pKa of p-nitrophenol is lower than the pKa of m-nitrophenol (7.2 vs.…

A: The stability of a conjugate base decides the acidity of a compound.

Q: Only two of the following carbonyl-containing compounds have a large equilibrium onstant for…

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Q: H b. . . C. d. i Hlor e. f. 2 H + H3C-C=N 1) NaOCzHg/C,H5OH 2) H₂O/H* NaOC₂H5 base & OH C2H5OH OH…

A: We have to draw the structure of the given products.

Q: CH3 CH3 1,3-dimethylbenzene with ethanoic anhydride and AICI3 to make CH3

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Q: Give the structure of the product from the reaction of propanal with 1M ethanol in dry acid . (…

A: Organic compounds are the compounds which are mainly composed C and H atoms. The branch of chemistry…

Q: reactivities of the following compounds according to the SN1 reaction. please explain why a) Methyl…

A: Many reaction mechanisms are studied in organic chemistry. The nucleophilic substitution mechanism…

Q: Provide the curved arrow formalins for tbe reaction of (R)-3-chloro-2-methyl-1-propanol treated with…

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Q: (d) . 1. `MgBr 1. O3 (2 equivalents) 2. Me2s 2. H20 K2Cr,O7 H2SO4 (2 equivalents) (d) Propose an…

A: Grignard reagent is mainly used to form new carbon-carbon bonds. Ozonolysis results in the cleave of…

Q: Determine the structures of compounds A-J in the following reaction sequences. 1. LIAIH4, ether В 2.…

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Q: Which reagents can be used to achieve synthesis of the Indicated target molecule? Conc. KMNO4/ H* /…

A: Given reaction is :  Which reagent can be used for the given synthesis = ?  Options are :

Q: 3-Bromocyclohexene is a secondary halide, and benzyl bromide is a primary halide. Both halides…

A: Given: To determine 3-Bromocyclohexene is a secondary halide, and benzyl bromide is a primary…

Q: The 1H NMR spectrum of N,N-dimethylformamide shows three singlets at 2.9, 3.0, and 8.0 ppm. Explain…

A: To explain this, 1) Draw the resonance structure of N,N-dimethylformamide. 2) Check whether rotation…

Q: c) The epoxide shown below gives a positive chromic acid test. Clearly explain this result. H3C. CH3…

A: The chromic acid test: It is a test given by carbonyl compounds in the presence of chromic acid. On…

Q: What series of reagents could be used to carry out the conversion shown? CI O C2/FeBr3;…

A: The first step is electrophilic substitution reaction, in which meta - chloro product is formed.  In…

Q: Give the major product when 2-bromobutanal reacts with acidic aqueous KCN.

A: the major product when 2-bromobutanal reacts with acidic aqueous KCN.

Q: Explain the problem o-hydroxy Benzene sulfonic acid is being subjected to Bromination. Clearly…

A: Given statement is :

Q: (m) DMP, CH2CI2 PCC, CH2CI2 Pyridinium chlorochromate in methylene chloride solvent Aco OAc -OAc OH…

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Q: If 6.1 ml of tert butyl chloride are involved in the friedel crafts alkyation reaction how many…

A: 6.1 ml of tert butyl chloride are involved in friedel crafts alkylation reaction. We have to…

Q: The infrared spectrum shown is consistent with which compound? 000 Benzaldehyde a. Ethyl benzoate b.…

A: By studying the exact IR peaks from spectra , structure determination can be done.

Q: Answer questions a-c about the Bronsted acid-base reaction below using the identifying letters A-D…

A: Only those acid -base reactions are feasible which forms weaker acid and base on product side as…

Q: Consider the following reaction schemes involving the reaction of an imine with an organolithium…

A: Non-bulky organolithiums like n-BuLi can undergo halogen exchange reaction as well as nucleophilic…

Q: 1-Bromo-2-methylpropane with sodium iodide in acetone

A: 1-Bromo-2-methylpropane can react with sodium iodide in acetone to form the major substituted…

Q: HO toluene, heat C10H12O4 CH3

A: This is the Diels Alder reaction .

Reactions of Ethers

Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.

Epoxides

Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.

Williamson Ether Synthesis

An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.