4. A chemist working for a drug company synthesizes four molecules that bind to the androgen receptor. You carry out a quantitative binding assay for each of these compounds using a purified androgen receptor preparation and determine the following K, values for the compounds: A. 1X 10*M B. 1X 10°M C. 2.5 X 10°M D. 1X 101°M Which of the compounds has the greatest affinity for the androgen receptor?
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- At 25C, 0.00188 g of AgCl dissolves in one liter of waterWrite a balanced chemical equationWhat is the formula for determining Ksp?What is the value of Ksp?.Determine values of Kc from the values of Kp given a. 2NO(g) + O2(g) ⇌ 2NO2(g) Kp = 1.48 x 104 at 184K b. Sb2S3(s) + 3H2 ⇌ 2Sb(s) + 3H2S(g) Kp = 0.429 at 713K"Calcium ions/oxalic acid equilibrium in the kidney" Base on the above statement, give an equilibrium related to that and answer the following questions: What is the K value of the equilibrium if it is available. Base on Le Chatelier's principle, when will that equilibrium will not meet and what negative effects will happen when the equilibrium is not met. Suggest the preventive measures that can be taken to avoid negative effects whem the equilbrium is not met.
- . At high temperatures, elemental nitrogen and oxygen react with each other to form nitrogen monoxide. N2(g)+O2(g)2NO(g)Suppose the system is analyzed at a particular temperature, and the equilibrium concentrations arc found to be [N2]=0.041M. [O2]=0.0078M, and [NO]=4.710M. Calculate the value of K for the reaction.When the reaction below reaches equilibrium, does the equilibrium lie on the left or the right side? Briefly explain. ClO– + CH3CO2H ⇌ HClO + CH3CO2– When the terminal phosphate is cleaved from the adenosine triphosphate molecule, the products are adenosine diphosphate and inorganic phosphate, ATP + H2O ––> ADP + Pi, where Pi stands for the various forms of phosphate that exist at the pH of the particular solution. If the total concentration of Pi is 2.5 x 10–2M, what are the concentrations of the predominant forms of phosphate that exist at pH 7.4? Permanganate, MnO4–, can act as an oxidizing agent in both acidic and basic aqueous solutions. Balance each of the following reactions by the half–reaction method, showing all steps in the balancing process. MnO4– + Al ––> MnO2 + Al(OH)4– in aqueous base MnO4– + CH3COOH ––> Mn+2 + CO2 in aqueous acidMyoglobin's reversible cycle of binding and releasing oxygen can be expressed as an equilibrium reaction by the following equation: MbO 2 Mb+O 2 . The value for in the myoglogin k_{1} oxygen reaction at 20 deg * C is 1.9 * 107M ^ - 1 * s ^ - 1 and the k_{-1} is 22M ^ - 1 * s ^ - 1 Calculate the value of the equilibrium constant.
- The equilibrium at 25 °C MaCl5 (aq) + 4 H2O (l) ↔ H3MaO4 (aq) + 5 HCl (aq) Kc = 5500 ΔH°(rxn) = 28.1 kJ/mol, Determine the ΔG°(rxn)Reaction: CrO42-(aq)+2H+(aq) <--> Cr2O72-(aq)+H2O(l) YELLOW ORANGE If sulfuric acid (H2SO4) is added to this solution, will a color change be observed? If so, how does the addition of sulfuric acid result in a color change? Explain your reasoning by showing the effect of the addition of H2SO4 on the equilibrium for the reaction.People who are both alcoholic andexposed to halogen compounds often die of liver failure. Whymight this be a logical ultimate result?
- ❤️❤️??helppppppA chemist at a pharmaceutical company is measuring equilibriumconstants for reactions in which drug candidatemolecules bind to a protein involved in cancer. The drugmolecules bind the protein in a 1:1 ratio to form a drug–proteincomplex. The protein concentration in aqueous solutionat 25 °C is 1.50 x 10-6 M. Drug A is introduced into the proteinsolution at an initial concentration of 2.00 x 10-6 M.Drug B is introduced into a separate, identical protein solutionat an initial concentration of 2.00x 10-6 M. At equilibrium,the drug A–protein solution has an A–protein complexconcentration of 1.00 x 10-6 M, and the drug B solutionhas a B–protein complex concentration of 1.40 x 10-6 M.Calculate the Kc value for the A–protein binding reactionand for the B–protein binding reaction. Assuming that thedrug that binds more strongly will be more effective, whichdrug is the better choice for further research?Calculate the equilibrium constant of the reaction in which glutamine is formed -O2CCH (NH3 +) CH2CH2CONH2 (hereinafter G) from glutamic acid -O2CCH (NH3 +) CH2CH2COOH (G ') in cells, under the action of the synthetase enzyme glutamine. This reaction is used to carry ammonia from the cells to the kidneys, where it is re-released and excreted. Use the value of the standard free reaction enthalpy G '(aq) + NH3 (aq) → G (aq) equal to +15.7 kJ / mol at 37 ° C. The reaction is driven by the feed-back of the ATP (aq) → reaction ADP (aq) + Pi (aq). the standard free enthalpy of which is -31 kJ / mol. What is constant equilibrium joint reaction: G '(aq) + NH3 (aq) + ATP (aq) → G (aq) + ADP (aq) + Pi (aq)?