For question 4, can you please confirm the correct stage? The earliest SARS-COV-2 infections in the United States were detected in the state of Washington in JanuaryStudent Worksheet (V2)2020. Scientists have since sequenced SARS-CoV-2 genomes from infected individuals throughout the country.Table 1 shows some sequence data for the gene that encodes the spike protein, which was sequenced fromSARS-COV-2 viruses collected in different states. (The last column of the table is left blank for you to fill in later.)The gene's sequence in the virus collected from Washington early in the pandemic is between 99% and 100%identical to that of viruses collected from Utah, Colorado, Kansas, and California later on. However, somemutations have occurred at specific locations in the gene over time.Table 1. Data on the sequences of spike proteins from SARS-CoV-2 viruses collected in different states from January to May2020. Note that during the process of amplifying and seguencing the viral RNA genomes, the RNA is converted to DNA. Datafrom GenBank.Position in the sequence alignmentNumber ofdifferencesState105930371440818060234032556328144WashingtonCCAGCUtahCCGColoradoCCAG$2KansasCT.CCCalifornia3. Which of the following types of mutations is represented in Table 1?substitutionsb. insertionsC.deletions4. At which stage of viral infection did these mutations most likely occur?uof nuclootide differences between the virus from

The spread of a dangerous virus within the body is called a viral infection. Tissue damage and the…

Answered: 4. At which stage of viral infection…

Biology Today and Tomorrow without Physiology (MindTap Course List)

5th Edition

ISBN:9781305117396

Author:Cecie Starr, Christine Evers, Lisa Starr

Publisher:Cecie Starr, Christine Evers, Lisa Starr

Chapter10: Biotechnology

Section: Chapter Questions

Problem 2CT

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Using PEN and PAPER ONLY, illustrate a SARS-CoV-2 genome organization showing all the genes.Label the 4 structural genes and the 2 genes that code for the PP1a and PP1b and produces 16nonstructural proteins.
How could sequencing many SARS-CoV-2 genomes be used to track how the virus has changed over time due to mutations?
Transmission studies suggest that there are at least three (3) different variants of the SARS-CoV-2 virus circulating in Latin America and the Caribbean. Discuss a recombinant DNA technology strategy that could be used to verify this claim.
Can you please pick the right answer in each parentheses? The spike protein of SARS-CoV-2 is a carbohydrate-modified protein that ["bind the RNA genome of the virus", "", "is on the surface of the viral particle", ""] and plays a role in both ["replication of the viral genome", "recognition of host cell"] and ["packaging of viral genome for export", "fusion of viral envelope with host cell plasma membrane"] . Importantly, earlier work on spike proteins from other corona viruses showed that this molecule ["remarkable resistance to immune response", "shows remarkable conformational changes"] and only one of these served as a good antigen for vaccine development. A critical discovery in advancing the development of our current vaccines was determining what changes in the amino acid sequence would ["block degradation of the spike protein", "stabilize the conformation of the protein found on the viral particle"]. This…
In the article "Sherlock: nucleic acid detection with CRISPR nucleases" by Max Kellner et al. (2020)Sherlock protocol (2).pdf Actions, authors explain in detail how CRISPR technology can be used to detect if a person is infected with SARS-CoV-2. In lecture, we mainly talked about CRISPR Cas9 but more Cas proteins have developed/discovered. Watch the following video that explain in more detail how Sherlock uses CRISPR technology to detect disease Which of the following statements are true:
The spread of the corona virus is now becoming enormous. In your point of view as a senior high school STEM student, what can you contribute or suggest to the government that will help in blessing the COVID-19 active casesin your community and flattening curve?
explain the full method you would use to sequence the full genome of SARS-Cov-2
Please help explain this sentence Identification of DAXX as a restriction factor of SARS-CoV-2 through a CRISPR/Cas9 screen Alice Mac Kain 1,12, Ghizlane Maarifi2,12, Sophie-Marie Aicher3, Nathalie Arhel 2, Artem Baidaliuk 4, Sandie Munier5,6, Flora Donati 5,6, Thomas Vallet 1, Quang Dinh Tran 1, Alexandra Hardy 1, Maxime Chazal 3, Françoise Porrot 7, Molly OhAinle 8, Jared Carlson-Stevermer 9, Jennifer Oki9, Kevin Holden 9, Gert Zimmer 10, Etienne Simon-Lorière 4, Timothée Bruel 7, Olivier Schwartz 7, Sylvie van der 5,6, Nolwenn Jouvenet 3✉, Sébastien Nisole 2✉, Marco Vignuzzi 1✉ &
In 1918, an influenza pandemic that originated with avian flu killed 50 million people. Researchers isolated samples of that virus from bodies of infected people preserved in Alaskan permafrost since 1918. From the samples, they sequenced the viral genome, then reconstructed the virus. The reconstructed virus is 39,000 times more infectious than modern influenza strains, and 100 percent lethal in mice. Understanding how this virus works can help us defend ourselves against other deadly influenza strains that arise. For example, discovering what makes it so infectious would help researchers design more effective vaccines. Critics of the research are concerned: If the virus escapes the containment facilities (even though it has not done so yet), it might cause another pandemic. Worse, terrorists could use the published DNA sequence and methods to make the virus for horrific purposes. Do you think this research makes us more or less safe?
Compare and contrast the genetic material of SARS-COV-2 and Influenza Type A Virus.
Please consider the figure attached i. The ordinate (i.e., 'y-axis') represents values for the C or G nucleotide base proportion in sequences (or, in this case, genomes).ii. Influenza viruses that infected birds or moved from birds to humans without spreading are characterised by higher A + U content relative to influenza viruses that infected humans for long time periods.iii. Influenza viruses adapted to human hosts are characterised by lower G + C content relative to influenza viruses that infected birds or moved from birds to humans without spreading. iv. Human and swine influenza A H1N1 strains evolved from a birdlike G + C state to a humanlike G + C state since 1918. v. Data such as those depicted in the figure have been interpreted as evidence that the 1918 influenza virus strain originated from a bird influenza virus population. Question 1 options: A) Statement ii conveys accurate information. B) Statements ii,…
What does the acronym CRISPR stand for? Briefly outline the components of the CRISPR/Cas system. What is the function of the CRISPR/Cas system?What do you think about the ethical impacts of a technology such as CRISPR? What is the main parameter that is used to define new virus families among archaeal viruses? List and outline that various stages through which bacteria and archaea fight back against infection with viruses.

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