4. Consider the following nucleophilic substitution:CH31) CH3O Na*CH3HO.2) H*"OCH3a. Is the reaction Sx1 or SN2?b. Draw the reaction mechanism to show how compound B is formed.c. Label the chiral centre(s) with R/S notation for compound B.d Give TWO uses of acid in this reaction.e. When acid is added first followed by addition of methanol, compound C, however,would be the major product of this reaction.CH31) H*2) CH3ОНOCH3CH3OHA,Which one is a stronger nucleophile? CH3ONA* or CH OH? Explain.ii.Is the reaction Sxl or SN2?iii.Draw the reaction mechanism to show how compound C is formed.

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4. Consider the following nucleophilic substitution: CH3 1) CH3O Na* CH3 HO, 2) H* COCH3 A a. Is the reaction Sx1 or SN2? b. Draw the reaction mechanism to show how compound B is formed. c. Label the chiral centre(s) with R/S notation for compound B.

4. Consider the following nucleophilic substitution: CH3 1) CH3O Na* CH3 HO, 2) H* COCH3 A a. Is the reaction Sx1 or SN2? b. Draw the reaction mechanism to show how compound B is formed. c. Label the chiral centre(s) with R/S notation for compound B.

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter15: Radical Reactions

Section: Chapter Questions

Problem 14E

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Concept explainers

Alkanes and Cycloalkanes

Alkanes are saturated organic compounds which are made up of C and H atoms. Alkanes have the general formula of CnH2n+2. Alkane contains sp3 hybridized carbon atoms with four sigmas (σ) bonds & every hydrogen atom is connected with one of the carbon atoms. The size of the alkane could be determined by the number of carbon atoms located in it.

Question

4. Consider the following nucleophilic substitution:
CH3
1) CH3O Na*
CH3
HO.
2) H*
"OCH3
a. Is the reaction Sx1 or SN2?
b. Draw the reaction mechanism to show how compound B is formed.
c. Label the chiral centre(s) with R/S notation for compound B.
d Give TWO uses of acid in this reaction.
e. When acid is added first followed by addition of methanol, compound C, however,
would be the major product of this reaction.
CH3
1) H*
2) CH3ОН
OCH3
CH3
OH
A,
Which one is a stronger nucleophile? CH3ONA* or CH OH? Explain.
ii.
Is the reaction Sxl or SN2?
iii.
Draw the reaction mechanism to show how compound C is formed.

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