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- 2. Myopia, also known as nearsightedness. Is a trait that is completely dominant over normal eyesight? Use letters N and n for two contrasting expressions of eyesight. a. What is the genotype of a pure-breeding myopic person? b. What is the genotype of a person with normal eyesight?3. In 1988, neurologists in Australia reported the existence of identical twins who had developed myoclonic epilepsy in their teens. One twin remainedonly mildly affected by this condition, but the othertwin later developed other symptoms of full-blownMERRF, including deafness, ragged red fibers, andataxia (loss of the ability to control muscles).Explain the phenotypic dissimilarity in theseidentical twins.2. One parent is homozygous for the allele for myostatin that results in big muscles and the other is homozygous for the allele that results in typical muscles (MM x mm). a. Part A (fill in the boxes): M M m m b. Part B (fill in the boxes): Total number of offspring with the heavily muscled phenotype Proportion and percent of heavily muscled offspring Total number of offspring with the in-between phenotype Proportion and percent of in-between offspring Total number of offspring with typical muscles Proportion and percent of typical muscled offspring Total: 100%
- Discuss the molecular players in myogenesis. Specify their role in the process.3. One parent is homozygous for the allele for myostatin that results in big muscles and the other parent is heterozygous (MM x Mm). a. Part A (fill in the boxes): M м M m b. Part B (fill in the boxes): Total number of offspring with the heavily muscled phenotype Proportion and percent of heavily muscled offspring Total number of offspring with the in-between phenotype Proportion and percent of in-between offspring Total number of offspring with typical muscles Proportion and percent of typical muscled offspring Total: 100%ntml 4 of 9 4. Huntington's disease affects the muscles and nervous system. People who hạve Huntington's'usually get the disease in their 30s. Which of the following is the most accurate statement? A. Huntington's disease could not be due to genetics because genes determine your inherited traits from birth and they do not change in your 30s. B. Huntington's disease could not be due to genetics because everyone's internal organs are the same. C. Huntington's disease could be due to genetics because a slight change in a gene you are born with produces an abnormal protein that eventually leads to a disease. D. Huntington's disease could be due to genetics because most diseases that affect the nervous system are due to genetics. Powered by Linklt!
- AaBbCcDdE AaBbCcDc AaBbC Normal No Spacing Heading 1 Head Activity 1. 3. Based on the following data which of the following would be considered: a. Recessive? b. Dominant? C. A weak loss-of-function mutation? d. A null mutation? e. A haploinsufficiency ? Data - Gene "B" is required for formation of body segments. A wild type fly had 3 body segments. BB (Homozygous dominant) Wild Type Bb (Heterozygous) bb (Homozygous recessive) Lacks all body segments 1 body segment Mutant 1 Wild Type Mutant 2 Wild Type 2 body segments Mutant 3 Wild Type Wild Type 2 body segments Activity 4 tv Ps X W 000 DII DD II1. During the formation of the limb bud, the components of the zeugopodium develop in the presence of: a. High concentrations of Fgf and low concentrations of Gli b. High expression of Hox genes 9 and 10 c. High expression of Hox genes 10 and 11 d. Intermediate concentrations of Retinoic Acid and Wnt e. Low concentrations of Retinoic Acid and Fgf f. a and b g. a and c h. c and d i. b and e6. In solving problems 1-4, you made some predictions of TRCs based on the genotypesof the individuals involved. Suppose we could measure the TRCs for some people withthose genotypes and found the actual values to be different from those predicted by yourcalculations. How would you explain these discrepancies?
- 5. Both parents are heterozygous (Mm x Mm) a. Part A (fill in the boxes): M m M b. Part B (fill in the boxes): Total number of offspring with the heavily muscled phenotype Proportion and percent of heavily muscled offspring Total number of offspring with the in-between phenotype Proportion and percent of in-between offspring Total number of offspring with typical muscles Proportion and percent of typical muscled offspring Total: 100%4. In the following cases, who will have more BMR and why? A_. A male with height of 5 feet six inches OR a male with height of 6 feet.1. (4) A fly cross. DDEE X DdEe, where D is long wings, d is short wings, and E is gray and e is ebony. Results: Long wing, gray 304 Long, ebony 79 Short wing, gray 82 Short, ebony 15 First, figure out what the "expected" ratios are, and then what the actual expected NUMBERS are. Do a Chi? to see if these numbers are close enough to the "expected" numbers, or is there something else going on. (Interpret the Chi square.) Show work! use Table I posted
