4. Why is it unwise to begin addition of the solution of carbonyl compound to the Grignard reagent before the latter has cooled to room temperature?

Q: Why aryl bromide is a bad starting material for an electrophilic aromatic substitution? What is…

A: For electrophilic aromatic substitution ,the phenyl ring should be electronically enriched as…

Q: What is the difference, in terms of chemical components, between Benedict's and Fehling's reagent?…

A: Interpretation: We have to tell the difference between Benedict's reagent and Fehling's reagent.

Q: why is 12 M HCl added to the reaction mixture after the Williamson Ether Synthesis r

A: Williamson ether synthesis is used to prepare both symmetrical and unsymmetrical ether. When sodium…

Q: Offer an explanation for the observation that 4-chloropyridine is more reactive toward nucleophiles…

A: The reason why 4-chloropyridine is more reactive towards nucleophiles when compared to…

Q: Why is a sulfonate anion such a good leaving group?

A: Those species which are weak base are good leaving group because they are poor electron donors. If…

Q: Why is it necessary to acidify the mixture obtained after reaction of Grignard reagent with both the…

A: Grignard reaction is an organometallic chemical reaction alkyl, aryl, vinyl or aryl magnesium…

Q: 2. (a) (E)- or trans-9-(2-phenylethenyl)anthracene and (Z)- or cis- 9-(2-phenylethenyl)anthracene…

A:

Q: Why is the presence of acid necessary in the reaction of carbonyl compounds with certain…

A: Reaction of carbonyl (suppose acetone) with nucleophile like 2,4-dinitrophenyl hydrazine follows…

Q: Why does the synthesis of grignard reagents require ethers when the synthesis of organolithium…

A: During the synthesis of any organometallic compound, we certainly require a solvent to dissolve the…

Q: Which solvent would be used for a reaction using a Grignard reagent (RMgX)?

A: The solvent with no acidic hydrogen is used in case of grignard reagent reaction.

Q: Why are the starting materials (Triphenyl Phosphine and Benzyl Chloride) soluble in xylene but the…

A: According to the solubility rule, like dissolve like , polar/ionic solvents dissolve polar/ionic…

Q: Explain how you would test the relative reactivities of 1‐butanol vs. 2‐butanol in a nucleophilic…

A: relative reactivities of 1‐butanol vs. 2‐butanol in a nucleophilic substitution with sodium bromide…

Q: Show two combinations of epoxide and Gilman reagent that can be used to prepare racemic…

A: Organocopper compounds: The Organocopper reagents react with alkyl, alkenyl and aryl halides to give…

Q: Why is anhydrous ether the preferred solvent during the synthesis of the Grignard reagent reaction…

A: We have to discuss  the reason of use the  anhydrous ether is the preferred solvent during the…

Q: is the sodium borohydride reduction of aldehydes selective?

A: Reducing agent are those which reduces the other and oxidise itself.

Q: 3. After addition of benzophenone, 6 M HCI is added to the Grignard reaction mixture. Why? Show the…

A: Answer:

Q: Name a typical organic solvent that would not be appropriate to use in the preparation of a Grignard…

A: Acid reacts with base to form salt and water. This reaction is known as neutralization reaction.

Q: why it is not a good idea to use dichloromethane as a solvent in Grignard reactions.

A: Reason for not using dichloromethane as a solvent in Grignard reactions.

Q: Why must the alkyl halide product be dried carefully with anhydrous sodium sulfate before the…

A: Given:-  Nucleophilic substitution reaction:                         The reaction of electron pair…

Q: Explain Reaction of Grignard Reagents with Carbon Dioxide ?

A: Grignard reagent It is also known as grignard compound. It has generic formula R-Mg-X. X is halogen.…

Q: What is the difference between activated pyridine and unactivated pyridine

A: Pyridine is a pi difficient heterocycle, pyridine ring is less nucleophilic than the benzenering…

Q: MgBr |. 2.

A:

Q: le 6.3 Observations on the reaction of each test sample with Baeyer's reagent.

A: Alkaline solution of potatium permangante ( alkaline solution of KMnO4 ) is called " Baeyer's…

Q: While attempting to recrystallize maleic anhydride, a student dissolved it in freshly distilled…

A: Cyclopentadiene is a conjugated diene that is used in the Diels alder Reaction. Diels Alder Reaction…

Q: This is the Maillard reaction to produce the Amadori compound. Explain what type of reaction…

A:

Q: Why is sodium hydroxide used in the smallest molar amount Explain the process of the "seeding"…

A: Since the NaOH is a strong base and it completely dissociates in an aqueous solution and produces a…

Q: Please explain why a dry solvent that is non acidic is needed to form a grignard reagent.

A: Given : A dry solvent that is non acidic is needed to form a Grignard reagent.

Q: Propose a synthesis using a reaction of a diazonium salt in at least one step of each conversion. a.…

A: In this question, we have to find out the correct answer of given problem by the help of the…

Q: What are the reagents/conditions needed for these transformations?

A: The condition needed for the above transformation is given in attached image.

Q: Give a possible equation you could use to prepare 2-methyl-2-phenyl-pentanal using a pinnakol…

A: Carbonyl compound can be prepared from diol using pinnacol rearrangement  Pinnacol rearrangement…

Q: 2. Grignard reagents are sources of "carbanion", a potent base and nucleophile. Write a reaction…

A:

Q: Why did the demonstrator add sodium sulfate (Na2SO4) to the dichloromethane layer after he had…

A: it is explained as:

Q: Briefly explain why diethyl ether is the solvent of choice for Grignard reactions.

A: Grignard reagents are the reagents which have the formula RMgX. Hence the grignard reagent is an…

Q: Why do you need a strong base like sodium hydroxide to extract 2napthol out of ether? because a…

A: 2-naphthol is insoluble in water. However, due to the O-H bond, it is a weak acid. Thus, on reaction…

Q: Complete these reactions involving lithium diorganocopper (Gilman) reagents

A:

Q: Provide the reagents for the following reactions.

A: since you have posted multiple questions in a single session we are entitled to answer only first…

Q: Why is benzene diazonium chloride not stored and is used immediately after its preparation?

A:

Q: How does washing with 10% sodium bicarbonate help to isolate ethyl cinnamate in each synthesis…

A: To answer how does washing with 10% sodium bicarbonate help to isolate ethyl cinnamate in each…

Q: 5. Briefly explain your answer to the previous question in terms of the merits or drawbacks of each…

A: The suitable reagent for the conversion of R(CO)Cl to R(CO)CH3, (CH3)2CuLi is used.

Q: The Cannizzaro reaction experiment 1- Put with the equation, the Catizaro reaction. 2- What is the…

A:

Q: Explain how these Grignard reagents would react with molecules of their own kind to “self-destruct.”

A: 3-Hydroxypropylmagnesium bromide has an acidic proton (the alcohol). Because Grignard reagents are…

Q: Why is it important to maintain equivalent proportions of reagents in adol condensation reaction of…

A:

Q: Reduction of Cinnamaldehyde lab What is the purpose of adding sodium bisulfite?

A: The dilute sodium bisulfite solution is used to form salt andbit is carried out by the addition…

Q: Give the identity of nucleophile used to reduce acetone with the following reaction: Acetone +…

A:

Q: Why are aldehydes more reactive with Schiff's Reagent and 2,4-dinitrophenylhydrazine than ketones?

A: In Schiff's reagent the sulfur in the bisulfite ion acts as a nucleophile and adds to the carbonyl…

Q: 1. Compare the mechanism of the addition of Grignard reagent and Witting reagent to the carbonyl…

A: Applying concept of organic synthesis.

Q: Which would be the best choice of base for a Claissen reaction with propyl acetate? sodium propoxide…

A: When two molecules of an ethyl acetate undergo condensation reaction, in presence of sodium ethoxide…

Q: 4..Provide an alternate synthesis to synthesize each of the products 1-phenyl-1-propanol and…

A: Alcohols we can prepare from alkene by acid catalysed hydration.  Using grignard reagent from…