1. Compare the mechanism of the addition of Grignard reagent and Witting reagent to the carbonyl compound. Show the similarities and the differences between the two mechanisms.

Q: True or False The synthesis of dibenzalacetone is an example of Aldol condensation The synthesis…

A: Soft nucleophile gives 1,4 addition.. But Hard nucleophile gives 1,2 addition reaction.. Example of…

Q: Trimethylphosphine is a stronger nucleophile than triphenylphosphine, but it is rarely usedto make…

A: Given data :   Trimethylphosphine is a stronger nucleophile than triphenylphosphine, but it is…

Q: Design a two step synthesis that converts 3-pentanone into 3'-pentyl acetate as shown below. H2 -CH3…

A: we can convert  one functional group to  another by various reaction pathway like substitution or…

Q: What reagent did you use alongside with the peroxide on the first reaction?

A: Here, I have shown all the reagents that are involved in reaction one with names.

Q: 1. Design two syntheses of the compound below using the Grignard reagent and a carbonyl compound.…

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Q: why is 12 M HCl added to the reaction mixture after the Williamson Ether Synthesis r

A: Williamson ether synthesis is used to prepare both symmetrical and unsymmetrical ether. When sodium…

Q: Offer an explanation for the observation that 4-chloropyridine is more reactive toward nucleophiles…

A: The reason why 4-chloropyridine is more reactive towards nucleophiles when compared to…

Q: Give a Grignard reaction where the following reagent will participate.

A: Grignard reagent is prepared by halocompounds reaction with magnesium. In these reactions, the bond…

Q: HNO3 Zn A B D H2SO4 HCI or

A: The benzene undergoes an electrophilic substitution reaction. It has a high electron density, as it…

Q: 2. Explain why tert-butyl chloride will undergo an Sw1 but not an Sw2 reaction process?

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Q: Why is a sulfonate anion such a good leaving group?

A: Those species which are weak base are good leaving group because they are poor electron donors. If…

Q: If a large excess of the nitrating reagent is added, does the product produced contain one nitro…

A: Given: Excess of Nitrating mixture To find: Product will have one nitro group or more than one nitro…

Q: Why is the presence of acid necessary in the reaction of carbonyl compounds with certain…

A: Reaction of carbonyl (suppose acetone) with nucleophile like 2,4-dinitrophenyl hydrazine follows…

Q: Draw the starting material that would be needed to make this product through an intramolecular…

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Q: + 2 å NaOH

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Q: A Grignard reagent can be produced by combining an alkyl bromide or alkyl chloride with...

A: Given :-  alkyl bromide or alkyl chloride + ? → Grignard reagent  To identify :-  missing reactant

Q: 2. Provide a synthetic approach for the following reactions. Make sure to do the retrosynthetic…

A: the given target molecule is 3° alcohol. This alcohol is prepared from a ketone and grignard…

Q: Provide the synthetic route for the following reaction?  (CH3)2CHCH2Br ----> (CH3)2CHCH2CH2CH2NH2

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Q: What must be done to OH to make it a good leaving group?

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Q: Cross-aldol reactions are a convenient route to synthesizing B-hydroxyketones and aß- unsaturated…

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Q: Explain why a nucleophilic reagent such as ethoxide adds to an alkyne more easily than it adds to an…

A: The unsaturated hydrocarbons are of two types namely alkenes and alkynes. The alkenes consist of at…

Q: Explain why Acetonitrile (CH3CN). Is a better solvent for SN2 reactions and methanol (CH3OH) is thr…

A: A solvent plays an important role in the mechanism of the reaction. As it helps in mixing the…

Q: Explain Reaction of Grignard Reagents with Carbon Dioxide ?

A: Grignard reagent It is also known as grignard compound. It has generic formula R-Mg-X. X is halogen.…

Q: SN1 reactions are better performed in protic solvents. Explain why the researchers could not perform…

A: In SN1 reaction, alky halide/sulphonate react with a weak nucleophile. In first step of reaction…

Q: Arrange the following alcohols in order of increasing rate of reaction with the Lucas reagent.

A: Lucas reagent is a solution made up of with Conc HCl + Anhydrous ZnCl2  It is used to distingiush…

Q: Explain the effect of the structure of the alkyl halide on elimination through E1 and E2.

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Q: 4. Why is it unwise to begin addition of the solution of carbonyl compound to the Grignard reagent…

A: Organic reactions are the chemical reactions in which certain organic compounds involve in chemical…

Q: он Synthesize the compound in 2 different ways using Grignard reagents and reactions

A: In the organic synthesis, suitable reagent converts the reactant into products. Reagents attacks…

Q: What are the reagents/conditions needed for these transformations?

A: The condition needed for the above transformation is given in attached image.

Q: С. Claisen condensation

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Q: LDA is the base of choice for carbonyl compound to completely convert into enolate. Why?

A: The full form of LDA is Lithium diisopropylamide. It has isopropyl groups create hindrance and make…

Q: three source of loss and compare the final product purity for Aldol Reaction-Preparation of…

A: Interpretation: To find three sources of loss in the given aldol reaction of acetone and…

Q: All are true or false   a) The initially formed b-hydroxy carbonyl compound loses water in a Aldol…

A: a) The initially formed b-hydroxy carbonyl compound loses water in a Aldol condensation. TRUE- In…

Q: Why is the carbon bonded to halogen electrophilic? Indicate with arrows the direction of…

A: Carbon is less electronegative than halogen atom.  Halogen atom has greater tendency to attract…

Q: 4. Give a short, efficient synthesis of the target compound from the indicated starting material and…

A: This reaction will be carried out by a (4+2) cycloaddition reaction which is a diels alder reaction…

Q: reagents

A: In Negishi cross coupling Reaction, Aryl halide or vinyl halide react with Organozinc to form…

Q: Explain why alkylation of an a-carbon works best if the alkyl halide used in the reaction is a…

A: The alkylation reaction of an α-carbon depends on the R-X (alkyl halide) used in the reaction. The…

Q: 5. Briefly explain your answer to the previous question in terms of the merits or drawbacks of each…

A: The suitable reagent for the conversion of R(CO)Cl to R(CO)CH3, (CH3)2CuLi is used.

Q: 1) Compare and contrast the similarities and differences between the mechanisms of the carbonyl…

A: According to Q&A guidelines of Bartleby, we are supposed to answer only the first 3 sub-parts of…

Q: Need help finding the order of Reagents  to form the product

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Q: 1. Why is aldol product the major product in relation to the Cannizzaro reaction?

A: Note: Since you have posted a question with multiple subparts, we will solve the first three…

Q: Explain why it is not possible to prepare tert-butyl phenyl ether using a Williamson ether…

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Q: From benzaldehyde, compunds of 2 carbons or less, and any inorganic reagent you want synthesize the…

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Q: 5.) E2 reactions and the Williamson Ether Synthesis use very similar reagents, yet yield different…

A: Williamson Synthesis : primary alkyl halide and strong base favors Williamson synthesis. E2…