A 42 yr old woman is not in shape but still decides to run a marathon. During the event, she collapses and is brought to the ER. Arterial blood gas analysis shows PO2 of 100 mmHg (normal), PCO2 of 42 mmHg (normal), and pH of 7.30 (low). Further evaluation reveals high anion-gap metabolic acidosis. Increased activity of which of the following biochemical pathways is the basis of the clinical findings? a. ETC b. Citric acid cycle c. Anaerobic glycolysis d. Beta-oxidation of fatty acids e. Mitochondrial oxidative phosphorylation
A 42 yr old woman is not in shape but still decides to run a marathon. During the event, she collapses and is brought to the ER. Arterial blood gas analysis shows PO2 of 100 mmHg (normal), PCO2 of 42 mmHg (normal), and pH of 7.30 (low). Further evaluation reveals high anion-gap metabolic acidosis. Increased activity of which of the following biochemical pathways is the basis of the clinical findings? a. ETC b. Citric acid cycle c. Anaerobic glycolysis d. Beta-oxidation of fatty acids e. Mitochondrial oxidative phosphorylation
Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter18: Glycolysis
Section: Chapter Questions
Problem 20P: Understanding the Mechanism of Hemolytic Anemia Genetic defects in glycolytic enzymes can have...
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