A method of quantitative determination of the concentration of constituents of a sample analyzed by gas chromatography is area normalization. This complete elution of all sample constituents is required. The area of each peak is measured and corrected for the detector response to the diffe- rentes eluatos. This correction involves dividing the area by an empiricalcorrection factor Determined. The concen ration of the analyte is found from the ratio between its corrected and the total corrected area of all peaks. For a chromatogram containing three relative areas were determined as 16.4; 45,2; and 30.2, in the order of increased retention time. Calculate the percentage of each compound if the relative responses from the detector are 0.65, 0.73 and 0.85, respectively.

Principles of Instrumental Analysis
7th Edition
ISBN:9781305577213
Author:Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Chapter27: Gas Chromatography
Section: Chapter Questions
Problem 27.26QAP
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A method of quantitative determination of the concentration of constituents
of a sample analyzed by gas chromatography is area normalization. This
complete elution of all sample constituents is required. The
area of each peak is measured and corrected for the detector response to the diffe- rentes
eluatos. This correction involves dividing the area by an empiricalcorrection factor
Determined. The concen ration of the analyte is found from the ratio between its
corrected and the total corrected area of all peaks. For a chromatogram containing three
relative areas were determined as 16.4; 45,2; and 30.2, in the order of
increased retention time. Calculate the percentage of each compound if the
relative responses from the detector are 0.65, 0.73 and 0.85, respectively.

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