A) The biotransformation of this drug: Choose all that apply. CH3 CH3 H,c-N. OH H,C OH он HO H,C. Phase I Phase II Reductive reaction Oxidative reaction Hydrolysis reaction glucuronic acid conjugation sulfate conjugation O methylation O acetylation product becomes less water soluble Porducts become more water soluble excretion of the products mostly happens in kidney excretion of the product mostly happens in feces B) What is the enzyme and coenzyme/cosubsrate ?

A) The biotransformation of this drug: Choose all that apply. CH3 CH3 H,c-N. OH H,C OH он HO H,C. Phase I Phase II Reductive reaction Oxidative reaction Hydrolysis reaction glucuronic acid conjugation sulfate conjugation O methylation O acetylation product becomes less water soluble Porducts become more water soluble excretion of the products mostly happens in kidney excretion of the product mostly happens in feces B) What is the enzyme and coenzyme/cosubsrate ?

Principles of Instrumental Analysis

7th Edition

ISBN:9781305577213

Author:Douglas A. Skoog, F. James Holler, Stanley R. Crouch

Publisher:Douglas A. Skoog, F. James Holler, Stanley R. Crouch

Chapter14: Applications Of Ultraviolet-visible Molecular Absorption Spectrometry

Section: Chapter Questions

Problem 14.15QAP

See similar textbooks

Similar questions

Carbonic anhydrase catalyzes the hydration of carbon dioxide: H2O + CO2 -> HCO3- + H+The following data is available: (image) - Calculate the Michaelis Menten constants - In the presence of sulfanilamide the Michaelis Menten constants for the reaction are Vmax: 7.57e-5M/s and Km: 20M. What type of compound is sulfanilamide and what is its mechanism of action?
please explain why this happends, im having trouble in this section. Part A Chymotrypsin, an enzyme that hydrolyzes peptide bonds in proteins, functions in the small intestine at an optimum pH of 7.7 to 8.0. How is the rate of the chymotrypsin-catalyzed reaction affected by each of the following conditions?
Which of the following is NOT a catalytic strategy used by carbonic anhydrases? a. metal ion catalysis b. catalysis by approximation c. Acid-base catalysis d. Formation of covalent intermediate
When some sugars dissolve in water they spontaneously undergo changes in optical rotation called mutarrotation. The Mutarrotation of D-glucopyranose is catalyzed by acid and bases. 2-Hydroxypyridine is a more effective catalyst than phenol and pyridine for this reaction because: a.Both oxygen and N in 2-hydroxypyridine act as bases increasing the rapid interconversion of sugar b. The OH of 2-hydroxypyridine serves as the base while the current N as the acid. c. 2-hydroxypyridine acts both as a base to remove the proton from the hydroxyl group in the hemiacetal and as an acid to provide a proton to the oxygen in the hemiacetal. d.Phenol and pyridine are very expensive.
Polyunsaturated fatty acids (PUFA's) in oils 0.g. sunflower oil are prone to rancidity because they contain conjugated double bond systems which are easily oxidized in the presence of light or peroxides. BHT Is used as an antioxidant in oils to prevent oxidative rancidity. How do BHT prevent oils from reacting with peroxides so that they do not become rancid? Show the mechanism.
Which group of side chains is most likely to take part in the catalysis during an enzymatic reaction? Substantiate the answer.
How did the rate change as the concentration of the S2O8-2 was halved. Expalin at molecular level.
Provide an electron pushing mechanism for the following ocidoreductase and hydrolyse catalyzed transofrmation. Use abbreviated catalyst active site groups (-B:, BH+) and co - factors as needed.
Suggest a mechanism of enzyme catalysed reaction.
Researchers at Rutgers University have developed biocompatible polymers that degrade into nonsteroidal antiinammatory drugs. For example, the reaction of two equivalents of benzyl salicylate and one equivalent of sebacoyl chloride forms a poly(anhydride ester) called PolyAspirin, which hydrolyzes to salicylic acid (an anti-inammatory agent) and sebacic acid, which is excreted. This technology can perhaps be used for localized drug delivery at specic sites of injury. What is the structure of PolyAspirin?
What is the mechanism of this reaction? Plz do Asap...!
This reaction is also an important reaction of the tricarboxylic acid cycle in cells, wherein the reaction occurs in neutral solution, so the acid groups are both ionized to the carboxylate form. The reaction is catalyzed by the stereospecific enzyme fumarase that utilizes only the trans form of 2-butenedioate ion (also known as fumarate) and produces only the (S)-2-hydroxysuccinate enantiomer (also known as (S)-malate). Draw the correct stereochemical structures of these two compounds of the fumarase-catalyzed reaction. Be sure to include all hydrogen atoms and show the carboxylates as anions.