A. DNA viruses generally cause malignancy by : inserting themselves in the host DNA, possible because their genome is similar to that of the host activating a cellular growth factor receptor, that activates the signal transduction pathway. inactivating a tumor suppressor gene, that results in uncontrolled proliferation. B. PDGF is overexpressed in certain cancers. This is an example of a mutation in the --- region a. regulatory b. coding

BIOLOGY:CONCEPTS+APPL.(LOOSELEAF)
10th Edition
ISBN:9781305967359
Author:STARR
Publisher:STARR
Chapter10: Control Of Gene Expression
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A. DNA viruses generally cause malignancy by :

  1. inserting themselves in the host DNA, possible because their genome is similar to that of the host
  2. activating a cellular growth factor receptor, that activates the signal transduction pathway.
  3. inactivating a tumor suppressor gene, that results in uncontrolled proliferation.

B. PDGF is overexpressed in certain cancers. This is an example of a mutation in the --- region

a. regulatory b. coding

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