a. Would you expect hemiacetals to be stable in basic solutions? Explain your answer.b. Acetal formation must be catalyzed by an acid. Explain why it cannot be catalyzed by CH3O-.c. Can the rate of hydrate formation be increased by hydroxide ion as well as by acid? Explain.

Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter23: Addition To A Carbonyl
Section: Chapter Questions
Problem 42CTQ
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a. Would you expect hemiacetals to be stable in basic solutions? Explain your answer.
b. Acetal formation must be catalyzed by an acid. Explain why it cannot be catalyzed by CH3O-.
c. Can the rate of hydrate formation be increased by hydroxide ion as well as by acid? Explain.

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