ABC2D z .C- X -0.2 kJ • mol- Y -12.3 kJ • mol-1 Z -1.2 kJ • mol-

Essentials of Pharmacology for Health Professions
7th Edition
ISBN:9781305441620
Author:WOODROW
Publisher:WOODROW
Chapter5: Abbreviations And Systems Of Measurement
Section: Chapter Questions
Problem 19CRQ
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A certain metabolic pathway can be diagrammed as (see pic1),  where A, B, C, and D are the intermediates, and X, Y, and Z are the enzymes that catalyze the reactions. The physiological free energy changes for the reactions are (see pic.2). Solve, (a) Which reaction is likely to be a major regulatory point for the pathway? (b) If your answer in Part a was in fact the case, in the presence of an inhibitor that blocks the activity of enzyme Z, would the concentrations of A, B, C, and D increase, decrease, or not be aff ected? 

ABC2D
z
.C-
Transcribed Image Text:ABC2D z .C-
X -0.2 kJ • mol-
Y -12.3 kJ • mol-1
Z -1.2 kJ • mol-
Transcribed Image Text:X -0.2 kJ • mol- Y -12.3 kJ • mol-1 Z -1.2 kJ • mol-
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