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Assume an enzyme has a loss-of-function mutation that completely abolishes the activity of that enzyme. Which of the following statements is true? A) If the enzyme catalyzes a reversible reaction, the loss-of-function mutation stops the flux through the pathway B) If the enzyme catalyzes a irreversible reaction, the loss-of-function mutation stops the flux through the pathway C) The levels of the products of the pathway with this enzyme will decrease (unless another pathway can generate the same products) D) The levels of the substrates of the pathway with this enzyme will increase (unless another pathway can use the same substrates) E) All of the above is true

Assume an enzyme has a loss-of-function mutation that completely abolishes the activity of that enzyme. Which of the following statements is true? A) If the enzyme catalyzes a reversible reaction, the loss-of-function mutation stops the flux through the pathway B) If the enzyme catalyzes a irreversible reaction, the loss-of-function mutation stops the flux through the pathway C) The levels of the products of the pathway with this enzyme will decrease (unless another pathway can generate the same products) D) The levels of the substrates of the pathway with this enzyme will increase (unless another pathway can use the same substrates) E) All of the above is true

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Assume an enzyme has a loss-of-function mutation that completely abolishes the activity of that enzyme. Which of the following statements is true? A) If the enzyme catalyzes a reversible reaction, the loss-of-function mutation stops the flux through the pathway B) If the enzyme catalyzes a irreversible reaction, the loss-of-function mutation stops the flux through the pathway C) The levels of the products of the pathway with this enzyme will decrease (unless another pathway can generate the same products) D) The levels of the substrates of the pathway with this enzyme will increase (unless another pathway can use the same substrates) E) All of the above is true
Transcribed Image Text:Assume an enzyme has a loss-of-function mutation that completely abolishes the activity of that enzyme. Which of the following statements is true? A) If the enzyme catalyzes a reversible reaction, the loss-of-function mutation stops the flux through the pathway B) If the enzyme catalyzes a irreversible reaction, the loss-of-function mutation stops the flux through the pathway C) The levels of the products of the pathway with this enzyme will decrease (unless another pathway can generate the same products) D) The levels of the substrates of the pathway with this enzyme will increase (unless another pathway can use the same substrates) E) All of the above is true
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