Achondroplasia is a dominant trait that causes a characteristicform of dwarfism. In a survey of 50,000 births, five infants withachondroplasia were identified. Three of these infants had parentswith achondroplasia, while two did not. Calculate the mutationrate for achondroplasia, and express the rate as the numberof mutant genes per given number of gametes.

Achondroplasia is a dominant trait that causes a characteristicform of dwarfism. In a survey of 50,000 births, five infants withachondroplasia were identified. Three of these infants had parentswith achondroplasia, while two did not. Calculate the mutationrate for achondroplasia, and express the rate as the numberof mutant genes per given number of gametes.

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Description: Achondroplasia is a dominant trait that causes a characteristicform of dwarfism. In a survey of 50,000 births, five infants withachondroplasia were identified. Three of these infants had parentswith achondroplasia, while two did not. Calculate the mu

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter16: Reproductive Technology, Genetic Testing, And Gene Therapy

Section: Chapter Questions

Problem 9QP: Cystic fibrosis is an autosomal disease that mainly affects the white population, and 1 in 20 whites...

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Achondroplasia is a dominant trait that causes a characteristic form of dwarfism. In a survey of 50,000 births, five infants with achondroplasia were identified. Three of the affected infants had affected parents, while two had normal parents. Calculate the mutation rate for achondroplasia and express the rate as the number of mutant genes per given number of gametes.
Table shows that Turner syndrome occurs when an individualinherits one X chromosome but lacks a second sex chromosome.Can Turner syndrome be due to nondisjunction duringoogenesis, spermatogenesis, or both? If a phenotypically normalcouple has a color-blind child (due to a recessive X-linkedallele) with Turner syndrome, did nondisjunction occur duringoogenesis or spermatogenesis in this child’s parents? Explainyour answer.
Cystic fibrosis is a recessive human condition. A male with Cystic fibrosis and a woman with a dominant phenotype have sevral children, in which one displays Cystic fibrosis. What can you conclude about the genotype of the maternal parent and what is the probability that a child who does not display Cystic fibrosis is heterozygous?
a human disease known as cystic fibrosis is inherited as a recessive trait.Two unaffected individuals have a first child with the disease. What isthe probability that their next two children will not have the disease?
A woman with achondroplasia (a dominant form of dwarfism) anda phenotypically unaffected man have seven children, all of whomhave achondroplasia. What is the probability of producing such afamily if this woman is a heterozygote? What is the probabilitythat the woman is a heterozygote if her eighth child does not havethis disorder?
In individuals affected by cystic fibrosis, salt crystals may appear afterperspiration dries up. In addition, the disease causes respiratory disorderswhich can be both debilitating and lethal. It occurs in individuals homozygousfor recessive gene. If 2 normal parents had a daughter with the symptoms ofthis disease, and a normal son, what is the probability that he might be acarrier of the recessive gene?Express answer in fraction form.
The gene for the production of eye colour in this species of fruit fly can be expressed aseither normal red-eyes or as brown-eyes. The allele for the normal red eyes is dominant tothat of brown, and is transmitted in normal Mendelian fashion.A gene involved with body colour in this species of fruit fly is located on the non-homologousportion of the X chromosome, and has two alleles, grey and yellow, where the grey allele isdominant to yellow.The two genes are NOT linked.a) Produce a key to clearly show the nature of the alleles associated with the eye colour inthis species of Drosophila, and in each case justify your choice of letters and / or style ofpresentation to best depict the genetics involved.
Identical twins are produced from the same sperm and egg (whichsplits after the first mitotic division), whereas fraternal twins areproduced from separate sperm and separate egg cells. If two parentswith brown eyes (a dominant trait) produce one twin boy with blueeyes, what are the following probabilities?A. If the other twin is identical, he will have blue eyes.B. If the other twin is fraternal, he or she will have blue eyes.C. If the other twin is fraternal, he or she will transmit the blueeye allele to his or her offspring.D. The parents are both heterozygotes.
Cystic fibrosis is an autosomal disease that mainly affects the white population, and 1 in 20 whites are heterozygotes. Genetic testing can diagnose heterozygotes. Should a genetic screening program for cystic fibrosis be instituted? Should the federal government fund it? Should the program be voluntary or mandatory, and why?
In C. elegans, lon-2 and unc-2 are recessive mutations that are 8 map units apart on the X chromosome. An hermaphrodite who is Lon and Unc is mated to a wild-type male. An F1 hermaphrodite is mated to a wild-type male. What are the expected percentages of the different phenotypes among the male progeny?
How many different types of gamete can be formed from an organism with the genotype AaBbccDDEeff, assuming independent assortment of all involved genes?
In humans, the genetic disease cystic fibrosis is caused by a recessive allele (a). The normal (healthy) allele is dominant (A). What is the genotype of someone who has cystic fibrosis? What are the two different genotypes that a healthy person could have? If two people were both heterozygous for the cystic fibrosis gene, what fraction of their children would be likely to have this disease? Hint: Draw a Punnett square to figure it out.