ADCC is an important mechanism for eliminating parasites and pathogen-infected cells. Go back and review the toxic materials present in eosinophils and NK cells (see Course Notes 2.1 and 2.2). List 5 of these toxins and state their effects on the target cells that have been tagged with antibodies. What kinds of antibodies are involved in triggering ADCC in each case (by eosinophils and by NK cells)?

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Immunology

Immunology is the division of science involved with the immune reactions occurring in living organisms. The organisms are accustomed to evolving internal defense mechanisms to evade the invasion of microbial pathogens. Diverse cells are connected with stimulating the immune responses, which produce inhospitable conditions to the microbes prompting their lysis and thus inhibits the multiplication of the pathogens. The immune system can distinguish the pathogens through the aid of cellular intercommunication and launch responses to destroy them.