What is an example of a biomolecule that interacts with Insulin? Please give a detailed explanation of that molecule's structure as well!
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- If phenylalanine was not an essential amino acid, would diet therapy (the elimination of phenylalanine from the diet) for PKU work?Consider fructose-1,6-bisphosphatase (FBP) when responding to Parts A, B, and C. When writing your response, please put A, B, or C in front of the answer for each part. NOTE: Each part can be answered in 3-4 sentences.A. State the effect (inhibition OR activation) of insulin signaling on the activity of FBP. Explain why this effect makes sense and make sure you identify the pathway where FBP participates.B. In a type 2 diabetic liver cell, when the blood sugar level is high, will the activity of FBP be HIGHER, LOWER, or THE SAME AS the activity in a nondiabetic liver cell under the same conditions? Explain your reasoning.C. Now think about the insulin and glucagon signaling pathways that control activity of FBP. When a nondiabetic liver cell is exposed to low blood sugar, indicate one specific way the insulin or glucagon signaling pathway could be disrupted so that the activity of FBP is not controlled correctly. Then, explain the reasoning for your answer.Define the different types of insulins and their naming schemes
- What is role of insulin in human body?One metabolic scenario that leads to insulin resistance is the elevation of the conccentration of free fatty acids in skeletal muscle cells. Would you expect increased activity of diacylglycerol acyltransferas (DGAT) to reduce or exacerbate the resistance? Explain.Will an amino acid be glucogenic or ketogenic if it is catabolized to the following molecules?(a) Phosphoenolpyruvate(b) -Ketoglutarate (c) Succinyl-CoA(d) Acetyl-CoA(e) Oxaloacetate(f) Acetoacetate
- What properties of glucokinase allow it to phosphorylate glucose in the liver when the blood glucose concentration is higher than normal?Describe how aspartate is degradedHow does the amino acid substitution and amino acid chain in protamine zinc insulin help control the rate at which insulin enters blood stream?