Assuming that glucose is burned to CO, as an energy source, how many amino acid residues can be incorporated into a protein mole- cule for each glucose consumed by a cell? Is this a maximum or min- imum estimate?
Q: Both hsp60-like and hsp70 molecular chaperonesshare an affinity for exposed hydrophobic patches on…
A: Molecular chaperones are defined as the proteins that aid or help in the folding or unfolding of…
Q: Experimental results describing a protein's amino acid composition are useful for estimating the…
A: Since you have asked multiple question, we will solve the first question for you. If you want any…
Q: Aspartate amino acids' pI values can be calculated as follows:
A: Aspartic acid is a standard amino acid and has a carboxylic group in its side chain. Due to the…
Q: , calculate the average amino acid residue weight in a protein of typical composition. This is a…
A: Proteins are composed of the linear chain of amino acids attached via peptide bonds. Proteins are…
Q: Given the following data, calculate Keq for the denaturation reaction of the protein β-lactoglobin…
A: Free energy change for a reaction, ΔG, can be solved using the standard change in Gibbs free energy,…
Q: TFQFPFAEQL EKVAEQFPTF QILNEEGEVV NEEAMPELSD EOLKELMRRM : (amino h (amino) (amino i (amino amg…
A: These six amino acid residues are split between two subunits. Together, they form a BASIC tunnel…
Q: Calculate the pI of (a) Ala, (b) His, and (c) Glu.
A: Alanine is an alpha amino acid that is used in the biosynthesis of proteins. It contains an amide…
Q: -0OC- pКа 3.2 -Co- CH pKa 4.& CH2 O *H,N-c-C H |
A: Amino acids are biomolecules that are composed of one alpha carbon bonded to 4 groups. These 4…
Q: Describe the two general metabolic fates of the carbon skeletons of amino acids.
A: Amino acids are biomolecules that are used to biosynthesize proteins. Several amino acids are joined…
Q: Define the term GABA (gamma-aminobutyric acid)?
A: GABA (Gamma Aminobutyric Acid ) is a natural occurring amino acid that work as a neurotransmitter in…
Q: What is the smallest number of molecules of ATP and GTP consumed in the synthesis of a 200- residue…
A: ATP is adenosine triphosphate and is an organic compound. It is a hydrotrope that provides energy to…
Q: What is the most consistently (i.e. found in every case) energetically unfavorable aspect of protein…
A: People have developed molecular dynamics simulations of the basic atomic forces that determine a…
Q: Suppose it were possible to label glucose with "C at any position or combination of positions. For…
A: Glucose is first converted into 2 molecules of pyruvate through glycolysis process. Pyruvate is then…
Q: The breakdown of a complex carbohydrate into its monomeric unit can be described as an…
A: Enzymes are catalysts that work by lowering the activation energy of the substrates. The lowered…
Q: What does this important observation imply about the relation between the amino acid sequence of…
A: Protein function is directly related to the structure of that protein. A protein's specific shape…
Q: A mature glycogen particle extends out from the homodimer, glycogenin, typically having 12 tiers of…
A: Glycogenin is an enzyme which catalyze the formation of glycogen from glucose. It is known that…
Q: An enzyme that catalyzes disulfide– sulfhydryl exchange reactions, called protein disulfide…
A: Protein disulfide isomerase or PDI is an enzyme that breaks sulfide bonds and is found in the…
Q: Hexokinase is an important enzyme in the metabolism of glucose. If theconcentration of hexokinase in…
A: Hexokinase phosphorylates the glucose in glycolysis which was a rate-limiting step that regulates…
Q: What is the likely keq for an enzyme that has a deltaG =-18.3kj/mol?
A: R = 8.314 J/K-mol R = 0.008314 kJ/K-mol Under standard conditions most enzyme have optimum activity…
Q: It is important to note that galactose is an important component of glyco- proteins. What is the…
A: Galactose is a hexose differing from glucose only by the hydroxyl group configuration at the…
Q: For the following concentrations, determine the equivalent of a. 75ug/mg lyophilized protein in ppm…
A: Proteins are a type of macromolecule that have a variety of roles in biological processes. It is…
Q: Calculate and compare the approximate MW of a protein with 682 amino acid residues in a single…
A: All the amino acids have an R group, H, COOH, and NH3.
Q: The enzyme hexokinase adds a phosphate toD-glucose but ignores its mirror image, L-glucose.…
A: Hexokinase is found in all metabolising cells of the body, whereas glucokinase is found in liver and…
Q: Consider a hexapeptide of the sequence thr asn glu trp lys gln. After complete hydrolysis, which…
A: Asked : Amino acid which elutes first
Q: Is a protein as good a cellular buffer at physiological pH as its constituent amino acids would be…
A: Since we only answer 1 question in case of multiple question, we’ll answer the first question as the…
Q: Correlation between lipid profile and Covid-19.Explain this statement.
A: In December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was discovered…
Q: Give the molecular basis of the observed mechanical properties of glutenin, a wheat storage protein…
A: Glutenin, a wheat storage protein rich in disulfide linkages and responsible for the cohesive and…
Q: Draw the Stable configuration of B-D-glucose
A: Glucose is a monosaccharide with molecular formula of C6H12O6. It is formed by green plants and…
Q: Sketch a titration curve for the amino acid cysteine, and indicate the pKavalues for all titratable…
A: Cystine is a proteogenic amino acid that has a thiol side chain. The thiol group of cysteine is…
Q: In preparation for the winter months, a squirrel gorges itself daily with 25g of blueberries (100 g…
A: Fructose can be converted to glucose and then converted to acetyl CoA 3.6 gm of fructose will get…
Q: The enzyme phosphoglucomutase interconverts glucose-1-phosphate and glucose-6-phosphate. Why is this…
A: Phosphoglucomutase (PGM) catalyzes the interconversion between glucose-1-phosphate (G-1-P) and…
Q: Give the molecular basis of the observed mechanical properties of glutenin, a wheat storage protein…
A: The gluten proteins are the major storage proteins found in wheat. These proteins are present in the…
Q: How does the presence of α-bonds versus β-bonds influence the digestibility of glucose polymers by…
A: Introduction: Carbohydrates are biomolecules that are comprised of carbon, hydrogen, and oxygen. It…
Q: Insulin possesses two polypeptide chains denoted A and B that are linked by disulfide bonds. Upon…
A: Insulin is composed of two subunits named as A and B. These subunits are attached with each other…
Q: How does the rate of achieving steady state and the ultimate steady state intracellular glucose…
A: Glucose is a protein that can be found on the plasma membrane. Transmembrane protein is another name…
Q: Which folate structure (from the list below)(a) is the substrate for the enzyme that is inhibited by…
A: Note: Since you have posted a question with multiple subparts, we will solve the first three…
Q: Calculate the pI of aspartate amino acids:
A: Introduction: Amino acids are macromolecule that contains two functional group amine and carboxyl.…
Q: List down the physiological significance of each of the 20 amino acids.
A: Amino acids: a. Amino acids are the building units of protein and other biomolecules. b. The key…
Q: Fish living in environments such as the Arctic Ocean, wherewater temperatures are below the freezing…
A: Introduction: Antifreeze glycoproteins (AFGPs) constitute the major fraction of protein in the blood…
Q: Can a pregnant cocker spaniel (dog) synthesize prostaglandin E2 from the dietary glucose? Yes or No.…
A: Prostaglandin E2 is considered a hormone, which plays a key role to induce labor during pregnancy.…
Q: . The process of a protein folding from an inactive unfolded structure to the active folded…
A: Amino acids interact with one another to give proteins. They require a well-defined 3D structure by…
Q: How does the presence of a-bonds versus B-bonds influence the digestibility of glucose polymers by…
A: The polymer form of glucose is found in polysaccharides which are the most abundant carbohydrates.…
Q: If both cysteine residues on the B chain of insulin were changes to alanine residues, how…
A: Insulin is made up of two chains A chain and B chain. Both the chains are linked together by two…
Q: Using the pk values, calculate the pl for each of the following: Isoelectric Amino acid/peptide…
A: Isoelectric point: The pH at which the net charge of the amino acid becomes zero is called iso…
Q: Why pl (isoelectric point) of amino acid with acidic or basic side chains is the average of the two…
A: Asked : pI average of pka reason
Q: What is/are the specific difference(s) between glucose and galactose? What is/are the…
A: Glucose, Galactose and Fructose are simple sugars that consist of single polyhydroxy aldehyde or…
Q: Based on the pk table for amino acids (Table 1.1), draw the structures with net charge, and the…
A: Acid strength is the tendency of an acid to dissociate and donate a proton. The value of pKa of an…
Q: The three pka values for the amino acid astrophan are: 1.9, 7.5, and 9.3. Calculate the isoelectric…
A: Given pKa's of three groups COO- ,R and NH3+ as 1.9,7.5 and 9.3 respectively. Also given protonation…
Q: Histidine is an amino acid containing an ionizable group in its side chain. This ionizable group has…
A: Histidine is an amino acid used in the biosynthesis of proteins. It is designated as “His” or only…
Step by step
Solved in 2 steps
- What is the molecular weight of the Botulinum neurotoxin, a protein that contains 1350 amino acids? Assume an average distribution of amino acidsHow many high-energy phosphates are generated or consumed in converting (a) 1 mole of glucose to lactate? (b) 2 moles of lactate to glucose?What does this important observation imply about the relation between the amino acid sequence of insulin and its three-dimensional structure?
- In a TPN bag contains: Kcal of 1000 ml of D50 W, 1000 ml of 7% amino acids, and 650 ml of 20% lipids. A. How many total kcal is provided by this bag of TPN?Commercially available high-energy formulas for premature infants are rich in triacylglycerols containing short- and medium-chain fatty acids esterified at the sn-3 position. Why?Calculate and compare the approximate MW of a protein with 682 amino acid residues in a single polypeptide chain and ahomotrimeric protein with 227 amino acid residues in each subunit.
- Experimental results describing a protein's amino acid composition are useful for estimating the molecular weight (MW) of the entire protein. A quantitative amino acid analysis reveals that bovine cytochrome c contains 6% alanine (?r 89.1) by weight. Calculate the approximate molecular weight of bovine cytochrome c if there are 6 alanine residues. Please enter your answer with three significant figures. approximate bovine cytochrome c MW: Da Bovine chymotrypsinogen has a molecular weight of 25.6 kDa. Amino acid analysis shows that this enzyme is 11% serine (?r 105). Calculate how many serine residues are present in a molecule of bovine chymotrypsinogen. Round your answer to the nearest whole number. number of serine residues:What is the smallest number of molecules of ATP and GTP consumed in the synthesis of a 200- residue protein, starting from amino acids? Assume that the hydrolysis of PP i is equivalent to the hydrolysis of ATP for this calculation.Given the following data, calculate Keq for the denaturation reaction of the protein β-lactoglobin at 25oC: ΔH° = –88 kJ/mol ΔS° = 0.3 kJ/mol. The free energy of hydrolysis of ATP in systems free of Mg2+ is −35.7 kJ/mol. When the concentration of this ion is 5 mM, ΔG°observed is approximately −31 kJ/mol at pH 7 and 38°C. Suggest a possible reason for this effect.
- Using the data in Table calculate the average amino acid residue weight in a protein of typical composition. This is a useful number to know for approximate calculationsA 0.0284 M aqueous solution of lactic acid, HC3H5O3, a substance that accumulates in the blood and muscles during physical activity, is found to be 6.7% ionized. Determine the value of Ka for lactic acid.Insulin possesses two polypeptide chains denoted A and B that are linked by disulfide bonds. Upon denaturation by reduction of the SH groups of insulin, followed by reoxidation, only 7% of the hormone activity is recovered. This is the level of activity expected for random pairing of cysteine residues to form disulfide bonds. How can these data be reconciled with the hypothesis that the amino acid sequence directs protein folding?