Both hsp60-like and hsp70 molecular chaperonesshare an affinity for exposed hydrophobic patches on pro-teins, using them as indicators of incomplete folding. Whydo you suppose hydrophobic patches serve as critical sig-nals for the folding status of a protein?

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter31: Completing The Protein Life Cycle: Folding, Processing, And Degradation
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Both hsp60-like and hsp70 molecular chaperones
share an affinity for exposed hydrophobic patches on pro-
teins, using them as indicators of incomplete folding. Why
do you suppose hydrophobic patches serve as critical sig-
nals for the folding status of a protein?

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