β-oxidation is inhibited by A. high acetyl-CoA levels B. low malonyl-CoA levels C. protein kinase A activity D. phosphorylation of acetyl-CoA carboxylase
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β-oxidation is inhibited by
| A. |
high acetyl-CoA levels |
|
| B. |
low malonyl-CoA levels |
|
| C. |
protein kinase A activity |
|
| D. |
phosphorylation of acetyl-CoA carboxylase |
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- Statin drugs are used to treat hypercholesterolemia because they a. prevent cholesterol from inserting in plasma membranes b. prevent cholesterol ester formation c. inhibit HMG-CoA reductase d. stimulate HMG-CoA synthaseWhich of the following stimulates the conversion of pyruvate to acetyl-CoA? a) Activation of pyruvate dehydrogenase kinase b) A decrease in the ratio of NAD+/NADH c) Bothaandb d) Neither a nor bAcetyl-CoA can be synthesized a. By pyruvate dehydrogenase or fatty acid ?-oxidation b. All the answers are true c. From pyruvate or fatty acids d. In the matrix of the mitochondria
- Not all of the acetyl-CoA from the mitochondria is carboxylated to malonyl-CoA because some are used in the? a.ß-oxidation cycles b.production of ATP c.priming step of the fatty acid biosynthesis d.conversion to pyruvateIf you fed a mouse a diet made up of exclusively Leucine, the mouse would eventually: A、Undergo extensive gluconeogenesis B、Enter ketosis C、Have a buildup of α-Ketoglutarate D、gain weight E、have a buildup of succinyl-CoAWhen one acetyl CoA is processed through the citric acid cycle, how many times does each of the following events occur? a. A FAD molecule is a reactant. b. A CoA-SH molecule is produced. c. A dehydrogenase enzyme is needed for the reaction to occur. d. A C5 molecule is produced.
- If your liver cells contained a mutation in ACC2 that rendered it constitutively inactive, what two downstream effects might you see as a result? Choose the TWO correct answers. (A) overproduction of malonyl CoA in the mitochondria (B) increase in ketone body synthesis(C) decreased rates of fatty acid oxidation(D) fewer VLDL particles produced by the liver (E) accumulation of fatty acyl-CoA in the cytoplasmThe initial step of the citric acid cycle is a. Conversion of pyruvate to acetyl-CoA b. Formation of ? -ketoglutarate catalysed by isocitrate dehydrogenase c. Condensation of acetyl-CoA with oxaloacetate d. Conversion of citrate to isocitrateThe reaction of acetyl-CoA and oxaloacetate in the TCA cycle forms a. 5-carbon α-ketoglutarate b. 4-carbon Succinyl-CoA c. 6-carbon citrate d. 6-carbon α-ketoglutarate e. 4-carbon citrate
- Acetyl-CoA carboxylase is inhibited by A. biotin B. citrate C. acetyl-CoA D. palmitateConsider the docosanoic acid, C21H43CO2H a. Label the a and B carbons b. Draw the acyl CoA derived from this fatty acid c. How many acetyl CoA molecules are formed by complete B-oxidation? d. How many cycles of B-oxidation are needed for complete oxidation? e. How many molecules of ATP are formed from the complete catabolism of this fatty acid?Which of the following citric acid cycle enzymes catalyzes substrate-level phosphorylation? A) isocitrate dehydrogenase B) α-ketoglutarate dehydrogenase C) succinyl CoA synthetase D) succinate dehydrogenase E) malate dehydrogenase