B. Briefly describe how can RNA seq be used to quantify differential gene expression between two types of tissues, e.g. normal vs cancer tissue. What is actually measured /counted to quantify the difference?

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Q: What are genetic screens?

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Q: suggest reasons for why DNA mutations are not all phenotypic.

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Q: Explain the genes responsible for complex diseases such as coronary artery disease ?

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Q: Define about Transgenic Large-Animal Models of Huntington Disease ?

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Q: Explain the loss-of-function mutation ?

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Q: What the grandparents' genotypes are? Why doesn’t the father (II-1) have the disease breast cancer?…

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Q: How would you relate the cancer cellular pathophysiology with genomic instability?

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Q: Give a diagram of how we can treatment the Cystic fibrosis by using gene therapy?

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Q: How would you relate the cancer cellular pathophysiology with genomic instability?

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Q: Identify An illness characterized by mutations that disrupt normal control mechanisms and produce…

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Q: Define common variants

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Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.