b. In the space below, develop a handout or diagram to explain how these checkpoints work under normal conditions. Your diagram should include a description of each checkpoint, where it acts in the cell cycle, and what each does to control cell division.

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Chapter10: Cell Reproduction
Section: Chapter Questions
Problem 17RQ: What is the main prerequisite for clearance at the G2 checkpoint? cell has reached a sufficient size...
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hello I'm asking for question 1B I already answered 1A & 1C

NameMuroaRoa Moreno
Course/Section.
Date
Professor/TA
Activity 18.4 What controls the cell cycle?
1. Checkpoints in the normal cell cycle prevent cells from going through division if
problems occur-for example, if the DNA is damaged.
a. What forms do the checkpoints take? That is, how do they control whether or not
cell division occurs?
Amimber of different cyclins are produced during interphase. 3 ofthe
major checkpoints in mitosis-the G,G, & Mphase cneciepoints-cppear
to bé contro1led by Caks (cyclin-deperdent Kinases).The ratio of cdks t their
CyClins determines their activity The activities of tne different activated
CdKs controlthe cell aycle, The cell can move past given'stage of theeycle
only when the agproprate cneckpoints cdk nas boenactivated.
b. In the space below, develop a handout or diagram to explain how these
checkpoints work under normal conditions. Your diagram should include a
description of each checkpoint, where it acts in the cell cycle, and what each does
to control cell division.
c. Cancer results from uncontrolled cell division. Explain how mutations in one or
more of the checkpoints might lead to cancer.
The basic function of each aneckpoint is to determine wnether or
not the cele is functioning normaluy &snould enter intor continue
through diision. If tnese checkpoirits break oloun , they could
allow any cell to Continue the cell cycle -that is, to diide
Cancer is uncontrolled cell division,so caner can result fronma
through
breakdouun of the operation of trese checkpoints.
Activity 18.4
Copyright © 2017 Pearson Education, Inc.
601
Transcribed Image Text:NameMuroaRoa Moreno Course/Section. Date Professor/TA Activity 18.4 What controls the cell cycle? 1. Checkpoints in the normal cell cycle prevent cells from going through division if problems occur-for example, if the DNA is damaged. a. What forms do the checkpoints take? That is, how do they control whether or not cell division occurs? Amimber of different cyclins are produced during interphase. 3 ofthe major checkpoints in mitosis-the G,G, & Mphase cneciepoints-cppear to bé contro1led by Caks (cyclin-deperdent Kinases).The ratio of cdks t their CyClins determines their activity The activities of tne different activated CdKs controlthe cell aycle, The cell can move past given'stage of theeycle only when the agproprate cneckpoints cdk nas boenactivated. b. In the space below, develop a handout or diagram to explain how these checkpoints work under normal conditions. Your diagram should include a description of each checkpoint, where it acts in the cell cycle, and what each does to control cell division. c. Cancer results from uncontrolled cell division. Explain how mutations in one or more of the checkpoints might lead to cancer. The basic function of each aneckpoint is to determine wnether or not the cele is functioning normaluy &snould enter intor continue through diision. If tnese checkpoirits break oloun , they could allow any cell to Continue the cell cycle -that is, to diide Cancer is uncontrolled cell division,so caner can result fronma through breakdouun of the operation of trese checkpoints. Activity 18.4 Copyright © 2017 Pearson Education, Inc. 601
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