Anatomy & Physiology
1st Edition
ISBN: 9781938168130
Author: Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble
Publisher: OpenStax College
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Textbook Question
Chapter 3, Problem 26RQ
What is a primary function of tumor suppressor genes?
- stop all cells from dividing
- stop certain cells from dividing
- help oncogenes produce oncoproteins
- allow the cell to skip certain phases of the cell cycle
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What is a primary function of tumor suppressor genes?a. stop all cells from dividingb. stop certain cells from dividingc. help oncogenes produce oncoproteinsd. allow the cell to skip certain phases of the cellcycle
Much remains unknown about the rapid, uncontrolled growth, or what causes a tumor to metastasize. Scientists do know that cancer cells come from normal healthy cells that have had some type of damage done to the genes that aid in the production of the regulatory proteins for the cell cycle. What causes this damage?
a
proto-oncogenes
b
mutations
c
enzymes
d
tumor suppressors
Which of the following is a trait that is detrimental to cancer cell progression?
Drug Resistance
Recognition by the immune system
Angiogenesis (growth of new blood vessels)
Deactivation of the tumor suppressor Rb
Chapter 3 Solutions
Anatomy & Physiology
Ch. 3 - Visit this link...Ch. 3 - Watch this video...Ch. 3 - Watch this video...Ch. 3 - Watch this video...Ch. 3 - Visit this link...Ch. 3 - Because they are embedded within the membrane, ion...Ch. 3 - The diffusion of substances within a solution...Ch. 3 - Ion pumps and phagocytosis are both examples of...Ch. 3 - Choose the answer that best completes the...Ch. 3 - Choose the term that best completes the following...
Ch. 3 - The rough ER has its name due to what associated...Ch. 3 - Which of the following is a function of the rough...Ch. 3 - Which of the following is a feature common to all...Ch. 3 - Which of the following organelles produces large...Ch. 3 - The nucleus and mitochondria share which of the...Ch. 3 - Which of the following structures could be found...Ch. 3 - Which of the following sequences on a DNA molecule...Ch. 3 - Place the following structures in order from least...Ch. 3 - Which of the following is part of the elongation...Ch. 3 - Which of the following is not a difference between...Ch. 3 - Transcription and translation take place in the...Ch. 3 - How many letters of an RNA molecule, in sequence,...Ch. 3 - Which of the following is not made out of RNA? the...Ch. 3 - Which of the following phases is characterized by...Ch. 3 - A mutation in the gene for a cyclin protein might...Ch. 3 - What is a primary function of tumor suppressor...Ch. 3 - Arrange the following terms in order of increasing...Ch. 3 - Which type of stem cell gives rise to red and...Ch. 3 - What multipotent stem cells from children...Ch. 3 - What materials can easily diffuse through the...Ch. 3 - Why is receptor-mediated endocytosis said to be...Ch. 3 - What do osmosis, diffusion, filtration, and the...Ch. 3 - Explain why the structure of the ER, mitochondria,...Ch. 3 - Compare and contrast lysosomes with peroxisomes:...Ch. 3 - Explain in your own words why DNA replication is...Ch. 3 - Why is it important that DNA replication take...Ch. 3 - Briefly explain the similarities between...Ch. 3 - Contrast transcription and translation. Name at...Ch. 3 - What would happen if anaphase proceeded even...Ch. 3 - What are cyclins and cyclin-dependent kinases, and...Ch. 3 - Explain how a transcription factor ultimately...Ch. 3 - Which of the following structures could be found...
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- are changes to the order of nucleotides in a segment of DNA that codes for a protein. Proto-oncogenes Tumor suppressor genes Gene mutations Negative regulatorsarrow_forwardFigure 10.13 Rb and other proteins that negatively regulate the cell cycle are sometimes called tumor suppressors. Why do you think the name tumor suppressor might be appropriate for these proteins?arrow_forwardBenign tumors: a. are noncancerous growths that do not spread to other tissues b. do not contain mutations c. are malignant and clonal in origin d. metastasize to other tissues e. none of thesearrow_forward
- ________ are changes to the nucleotides in a segment of DNA that codes for a protein. a. Proto-oncogenes b. Tumor suppressor genes c. Gene mutations d. Negative regulatorsarrow_forwardHow can errors in the cell cycle lead to cancer in humans?arrow_forwardWhich of the following statements about cancer is false? (a) oncogenes arise from mutations in proto-oncogenes (b) tumor suppressor genes normally interact with growth-inhibiting factors to block cell division (c) more than 120 cancer-driving genes have been discovered (d) oncogenes were first discovered in mouse models for cancer (e) the development of cancer is usually a multistep process involving both oncogenes and mutated tumor suppressor genesarrow_forward
- Explain the difference between a proto-oncogene and a tumor suppressor gene.arrow_forwardAnother model, the random model, proposes that any cell in a malignant tumor has the potential to form a new tumor. Does the cancer stem cell hypothesis contradict this idea?arrow_forwardApoptosis can occur in a cell when the cell is damaged no longer needed infected by a virus all of the abovearrow_forward
- A gene that codes for a positive cell cycle regulator is called a(n) _______. a. kinase inhibitor b. tumor suppressor gene c. proto-oncogene d. oncogenearrow_forwardA scientist notices that a cancer cell line fails to die when he adds an inducer of apoptosis to his culture of cells. Which hypothesis could explain why the cells fail to die? The cells have a mutation that prevents the initiation of apoptosis signaling. The cells have lost expression of the receptor for the apoptosis-inducing ligand. The cells overexpress a growth factor pathway that inhibits apoptosis. All of the above.arrow_forwardWhich of the following mutations will result in cancer? a. homozygous recessive mutation in a tumor-suppressor gene coding for a nonfunctional protein b. dominant mutation in a tumor-suppressor gene in which the normal protein product is overexpressed c. homozygous recessive mutation in which there is a deletion in the coding region of a proto-oncogene, leaving it nonfunctional d. dominant mutation in a proto-oncogene in which the normal protein product is overexpressedarrow_forward
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What are Mutations and what are the different types of Mutations?; Author: Science ABC;https://www.youtube.com/watch?v=I16YlE8qTBU;License: Standard youtube license