Begining with 1 M concentrations of each reactant and product at pH=7 and 25.0 degrees C, calculate the K'eq (to one decimal point) of the reaction Pyruvate + NADH+H+ <=> Lactate + NAD+.Note the temperature of this reaction will not affect the standard reducton potential delta E'o in the table 13-7b.please provide a comprehensive explanation with each step taken. TABLE 13-7bStandard Reduction Potentials of Some Biologically Important Half-ReactionsHalf-reactionE" (V)Pyruvate + 2H+ 2e → lactate--0.185Acetaldehyde + 2H+ + 2e → ethanol-0.197FAD + 2H+ + 2e- → FADH₂-0.219aGlutathione + 2H+ + 2e → 2 reduced glutathione-0.23S + 2H+ + 2e → H₂S-0.243Lipoic acid + 2H+ + 2e → dihydrolipoic acid-0.29NAD+ + H+ + 2e → NADH-0.320NADP+ + H+ + 2e- → NADPH-0.324-0.346Acetoacetate + 2H+ + 2e → B-hydroxybutyratea-Ke glutarate + CO₂ + 2H+ + 2e → isocitrate-0.382H+ + 2e → H₂ (at pH 7)-0.414Ferredoxin (Fe³+) + e- → ferredoxin (Fe²+)-0.432Source: Data mostly from R. A. Loach, in Handbook of Biochemistry and Molecular Biology, 3rd edn (G. D. Fasman, ed.), Physicaland Chemical Data, Vol. 1, p. 122, CRC Press, 1976.This is the value for free FAD; FAD bound to a specific flavoprotein (e.g., succinate dehydrogenase) has a different E" that dependson its protein environment. TABLE 13-7a Standard Reduction Potentials of Some Biologically Important Half-ReactionsHalf-reactionE° (V)¹/2 O₂ + 2H+ + 2e- → H₂O0.816Fe³+ + e Fe²+0.771NO3 + 2H+ + 2e → NO₂ + H₂O0.421Cytochrome f (Fe³+) + e- → cytochrome f (Fe²+)0.365Fe(CN)63- (ferricyanide) + e- → Fe(CN)64-0.360.35Cytochrome a3 (Fe³+) + ¯ → cytochrome a3 (Fe²+)O₂ + 2H+ + 2e → H₂O₂0.2950.290.254Cytochrome a (Fe³+) + e- → cytochrome a (Fe²+)Cytochrome c (Fe³+) + e- cytochrome c (Fe²+)Cytochrome (Fe³+) + e- → cytochrome c₁ (Fe²+)Cytochrome b (Fe³+) + e- → cytochrome b (Fe²+)Ubiquinone + 2H+ + 2e¯ → ubiquinol0.220.0770.045Fumarate² + 2H+ + 2e → succinate2-0.0310.0002H+ + 2e → H₂ (at standard conditions, pH 0)Crotonyl-CoA + 2H+ + 2e → butyryl-CoA-0.015Oxaloacetate²- + 2H+ + 2e → malate²--0.166Source: Data mostly from R. A. Loach, in Handbook of Biochemistry and Molecular Biology, 3rd edn (G. D. Fasman, ed.), Physicaland Chemical Data, Vol. 1, p. 122, CRC Press, 1976.This is the value for free FAD; FAD bound to a specific flavoprotein (e.g., succinate dehydrogenase) has a different Eº that dependson its protein environment.

Introduction: The term equilibrium constant (Keq) shows us the relationship between reactants and…

Begining with 1 M concentrations of each reactant and product at pH=7 and 25.0 degrees C, calculate the K'eq (to one decimal point) of the reaction Pyruvate + NADH+H+ <=> Lactate + NAD+. Note the temperature of this reaction will not affect the standard reducton potential delta E'o in the table 13-7b. please provide a comprehensive explanation with each step taken

Begining with 1 M concentrations of each reactant and product at pH=7 and 25.0 degrees C, calculate the K'eq (to one decimal point) of the reaction Pyruvate + NADH+H+ <=> Lactate + NAD+. Note the temperature of this reaction will not affect the standard reducton potential delta E'o in the table 13-7b. please provide a comprehensive explanation with each step taken

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter18: Glycolysis

Section: Chapter Questions

Problem 12P

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