Below is the procedure described for determination of paracetamol according to BP: "Weigh and powder 20 tablets. Add a quantity of powder equivalent to about 0.35 paracetamol to 50 ml of 0.1 M NaOH, dilute with water to 200 ml and shake for 15 min. Add sufficient water to make up 250 ml. Filter the solution and dilute 5 ml of the filtrate to 100 ml 6. with water. Dilute further 10 ml to 100 ml. Measure the absorbance at 257 nm. The A,% = 715 at 257 nm". Which of the following is correct? O a. An analyst can take 0.37g of the powdered tablets instead of 0.35. O b. An analyst can replace NAOH with HCI O C. An analyst can skip the shaking step O d. B andC e. All of the above

Chemistry
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Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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Below is the procedure described for determination of paracetamol according to BP:
"Weigh and powder 20 tablets. Add a quantity of powder equivalent to about 0.35 g
paracetamol to 50 ml of 0.1 M NaOH, dilute with water to 200 ml and shake for 15 min. Add
sufficient water to make up 250 ml. Filter the solution and dilute 5 ml of the filtrate to 100 ml
with water. Dilute further 10 ml to 100 ml. Measure the absorbance at 257 nm. The A, = 715
at 257 nm". Which of the following is correct?
O a. An analyst can take 0.37g of the powdered tablets instead of 0.35.
O b. An analyst can replace NaOH with HCl
O c. An analyst can skip the shaking step
O d. B andC
O e. All of the above
Transcribed Image Text:Below is the procedure described for determination of paracetamol according to BP: "Weigh and powder 20 tablets. Add a quantity of powder equivalent to about 0.35 g paracetamol to 50 ml of 0.1 M NaOH, dilute with water to 200 ml and shake for 15 min. Add sufficient water to make up 250 ml. Filter the solution and dilute 5 ml of the filtrate to 100 ml with water. Dilute further 10 ml to 100 ml. Measure the absorbance at 257 nm. The A, = 715 at 257 nm". Which of the following is correct? O a. An analyst can take 0.37g of the powdered tablets instead of 0.35. O b. An analyst can replace NaOH with HCl O c. An analyst can skip the shaking step O d. B andC O e. All of the above
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