Cytosol Mitochondrion A. PATHWAY 1. major pathway of ethanol metabolism NAD* NADH + H* NAD* NADH + H* in the liver CH,-CH,-OH ADH + CH,-C=O CH;-C-OH + H-O-H ALDH ETHANOL ACETALDEHYDE АСЕТАТЕ WATER B. PATHWAY 2 microsomal ethanol CYP2E1 oxidizing system (MEOS) NADPH + H* + O2 NADP* + 2H,O Excess alcohol consumption increases the NADH:NAD* ratio in the cytosol of hepatocytes. Q3: Based on the chemical structure, predict how permeable a biological membrane will be to ethanol (in the absence of a transporter/channel)? Q4: The conversion of ethanol to acetaldehyde and acetaldehyde to acetate in Pathway 1 is best classified as which type of reaction?

Anatomy & Physiology
1st Edition
ISBN:9781938168130
Author:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble
Publisher:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble
Chapter24: Metabolism And Nutrition
Section: Chapter Questions
Problem 6RQ: The Krebs cycle converts ________ through a cycle of reactions. In the process, ATP, ________, and...
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Cytosol
Mitochondrion
A. PATHWAY 1.
major
pathway of
ethanol
metabolism
NAD* NADH + H*
NAD* NADH + H*
in the liver CH,-CH,-OH ADH + CH,-C=O
CH;-C-OH + H-O-H
ALDH
ETHANOL
ACETALDEHYDE
АСЕТАТЕ
WATER
B. PATHWAY 2
microsomal
ethanol
CYP2E1
oxidizing
system
(MEOS)
NADPH + H* + O2
NADP* + 2H,O
Excess alcohol consumption increases the NADH:NAD* ratio in the cytosol of hepatocytes.
Transcribed Image Text:Cytosol Mitochondrion A. PATHWAY 1. major pathway of ethanol metabolism NAD* NADH + H* NAD* NADH + H* in the liver CH,-CH,-OH ADH + CH,-C=O CH;-C-OH + H-O-H ALDH ETHANOL ACETALDEHYDE АСЕТАТЕ WATER B. PATHWAY 2 microsomal ethanol CYP2E1 oxidizing system (MEOS) NADPH + H* + O2 NADP* + 2H,O Excess alcohol consumption increases the NADH:NAD* ratio in the cytosol of hepatocytes.
Q3: Based on the chemical structure, predict how permeable a biological membrane will be
to ethanol (in the absence of a transporter/channel)?
Q4: The conversion of ethanol to acetaldehyde and acetaldehyde to acetate in Pathway 1 is
best classified as which type of reaction?
Transcribed Image Text:Q3: Based on the chemical structure, predict how permeable a biological membrane will be to ethanol (in the absence of a transporter/channel)? Q4: The conversion of ethanol to acetaldehyde and acetaldehyde to acetate in Pathway 1 is best classified as which type of reaction?
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