Suppose a mutant Fatty Acid synthase only synthesizes a FA 14 Carbons long. How many ATP will the synthesis of this FA require (assume we're starting with Acetyl-CoA as our starting point)? 0 6 O 14 O 12
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- Understanding Enzyme Mechanisms Related to Pyruvate Carboxylase Based on the mechanism for pyruvate carboxylase (Figure 22.3), write reasonable mechanisms for the reactions that follow:The Effect of lodoacetic Acid on the Glyceraldehyde-3-P Dehydrogenase Reaction (Integrates with Chapters 4 and 14.) How might iodoacetic acid affect the glyceraldehydes-3-phosphate dehydrogenase reaction in glycolysis? Justify your answer.Account for the total no. of ATPs produced from β-oxidation for one mole of the given fatty acid (16C). How many acetyl-coA are formed?
- In the beta oxidatiin pathway when the starting fatty acid contains n carbons what is the priduct of the enzyme acyl-CoA sythetase assume the starting saturated fatty acud contains n carbons and n is an even numberHow many molecules of acetyl-CoA result from catabolism of 1 molecule of glyceryl trilaurate? (Hint: See Worked Example 24.3 and don’t forget glycerol.)Fatty acids are oxidized by acyl COA dehydrogenase. Branched fatty acids, containing a methyl group at beta carbons cannot be oxidized by this enzyme. How does the oxidation of such branched fatty acids take place? Explain with all set of reactions and enzymes involved.. give necessary detail.. avoid cpy righting
- Water production from fatty acid oxidation is a survival mechanism in animals where water is scarce. Cells oxidize palmitoyl-CoA to produce water. If an animal has 5.000 kg of palmitoyl-CoA available for fatty acid oxidation, how many kilograms of water could the animal produce from that palmitoyl-CoA? The chemical formula for palmitoyl-CoA is C37H66N7O17P3S.In considering the carbohydrate maltose... a. How many molecules of acetyl CoA are formed from its complete catabolism? b. How many rounds of Citric acid Cycle must occur to complete catabolism? c. How many rounds of electron transport chain and oxidative phosphorylation?Considering the complete oxidation of an 18-C fatty acid. Give the answer for the following question.a. How many rounds of beta-oxidation is needed?b. How many NADH molecules are produced in beta-oxidation only?c. How many FADH2 molecules are produced in beta-oxidation only?d. How many Acetyl Co-A are produced?
- Considering the complete oxidation of an 18-C fatty acid. Give the answer to the following question.a. What is the total number of NADH produced in TCA if all of the acetyl CoA enters the cycle? b. What is the total number of FADH2 produced in TCA if all the acetyl CoA enters the cycle?c. How much ATP is produced in the overall oxidation?Consider the docosanoic acid, C21H43CO2H a. Label the a and B carbons b. Draw the acyl CoA derived from this fatty acid c. How many acetyl CoA molecules are formed by complete B-oxidation? d. How many cycles of B-oxidation are needed for complete oxidation? e. How many molecules of ATP are formed from the complete catabolism of this fatty acid?The first step of gluconeogenesis involves the carboxylation of pyruvate and has a large negative delta G (i.e very exergonic). Explain how it is possible that this step can be exergonic if we know that adding CO2 onto molecules is fundamentally a destabilizing phenomenon?