4. PI3K is a lipid kinase that acts as a signal transducer. (a) What is the most well-characterized product of the PI3K-catalyzed reaction? (b) Explain why PTEN is classified as a tumor suppressor, being sure to describe its specific catalytic function in your response. PTEN is an inhibitor of PI3K thereby blocks PI3K/AKT/mTORC1 pathway that promotes cell growth.

4. PI3K is a lipid kinase that acts as a signal transducer. (a) What is the most well-characterized product of the PI3K-catalyzed reaction? (b) Explain why PTEN is classified as a tumor suppressor, being sure to describe its specific catalytic function in your response. PTEN is an inhibitor of PI3K thereby blocks PI3K/AKT/mTORC1 pathway that promotes cell growth.

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter9: Cell Communication

Section: Chapter Questions

Problem 19RQ: A scientist notices that a cancer cell line fails to die when he adds an inducer of apoptosis to his...

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