C Percentage Percentage 150 100 50 150 100 50 SARS-CoV-2 (anti-NP) → Cell viability PB28 ₂ -8 -7 -6 -5 PD144418 # -6 -5 log, [drug (M)] 150- 100 50 0 150₁ 100 50 0 -8 Haloperidol -6 -5 Clemastine HH -7 -6 -5 log₁o[drug (M)] 150- 100 50 150 100 50 Cloperastine -8 -7 -6 -5 Hydroxychloroquine -8 -7 -6 -5 log, [drug (M)] -4 For the Red data which has a square symbol data that we looked at in class, the Y axis is the percent of virus that remains free. The black data that has upside down triangles is a human cell line assay for viability. concentration results in a fraction For the drug Cloperastine, what micromolar (UM) bound (theta) of 0.25?
C Percentage Percentage 150 100 50 150 100 50 SARS-CoV-2 (anti-NP) → Cell viability PB28 ₂ -8 -7 -6 -5 PD144418 # -6 -5 log, [drug (M)] 150- 100 50 0 150₁ 100 50 0 -8 Haloperidol -6 -5 Clemastine HH -7 -6 -5 log₁o[drug (M)] 150- 100 50 150 100 50 Cloperastine -8 -7 -6 -5 Hydroxychloroquine -8 -7 -6 -5 log, [drug (M)] -4 For the Red data which has a square symbol data that we looked at in class, the Y axis is the percent of virus that remains free. The black data that has upside down triangles is a human cell line assay for viability. concentration results in a fraction For the drug Cloperastine, what micromolar (UM) bound (theta) of 0.25?
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
Related questions
Question
4
![• SARS-COV-2 (anti-NP)
- Cell viability
PB28
Haloperidol
Cloperastine
150,
150
150
100
100
100
50
50
50
-5
-6
-5
-7
-6
150
PD144418
150,
Clemastine
150, Hydroxychloroquine
100
100
100
50
50
50
-5
log,oldrug (M)
-7
-6 -5
log,,[drug (M)]
-8
-7
-6
-5
log,,[drug (M)]
For the Red data which has a square symbol data that we looked at in class, the Y axis is the
percent of virus that remains free. The black data that has upside down triangles is a
human cell line assay for viability. For the drug Cloperastine, what micromolar (uM)
concentration results in a fraction bound (theta) of 0.25?](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F5358406c-dd3d-4a14-85e1-5487256102eb%2F0907c6e9-9c71-4b83-b6c0-04a74b2aa9d6%2Fsry0m9_processed.jpeg&w=3840&q=75)
Transcribed Image Text:• SARS-COV-2 (anti-NP)
- Cell viability
PB28
Haloperidol
Cloperastine
150,
150
150
100
100
100
50
50
50
-5
-6
-5
-7
-6
150
PD144418
150,
Clemastine
150, Hydroxychloroquine
100
100
100
50
50
50
-5
log,oldrug (M)
-7
-6 -5
log,,[drug (M)]
-8
-7
-6
-5
log,,[drug (M)]
For the Red data which has a square symbol data that we looked at in class, the Y axis is the
percent of virus that remains free. The black data that has upside down triangles is a
human cell line assay for viability. For the drug Cloperastine, what micromolar (uM)
concentration results in a fraction bound (theta) of 0.25?
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