Calculate probability of sex-linked phenotypes of multiple offspring using binomial expansion NLGN3 is located in the X chromosome and a recessive variant (R451C) has been linked to Autism Spectrum disorder. A man with the R451C variant and Asperger syndrome has two sons with a woman without the variant and no ASD. What is the probability that both sons have ASD?

Science Of Agriculture Biological Approach
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ISBN:9780357229323
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Calculate probability of sex-linked phenotypes of multiple offspring using binomial expansion
NLGN3 is located in the X chromosome and a recessive variant (R451C) has been linked to Autism
Spectrum disorder. A man with the R451C variant and Asperger syndrome has two sons with a woman
without the variant and no ASD.
What is the probability that both sons have ASD?
Transcribed Image Text:Calculate probability of sex-linked phenotypes of multiple offspring using binomial expansion NLGN3 is located in the X chromosome and a recessive variant (R451C) has been linked to Autism Spectrum disorder. A man with the R451C variant and Asperger syndrome has two sons with a woman without the variant and no ASD. What is the probability that both sons have ASD?
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