For a typical cell that is 100 times more permeable to K* than to any other ion, use the Goldman equation to determine the potential change that would be produced by a doubling of the extracellular K+ concentration. (Use appropriate concentrations from the previous question). HINTS: Use 58 in the Goldman equation for results in mV or 0.058 for results in V. Because this problem is about change (one value relative to another), you do not need to know the permeabilities of individual ions; you only need to know that PK is 100 times higher than PNa and PCI.

Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter4: Principles Of Neural And Hormonal Communication
Section: Chapter Questions
Problem 3SQE
icon
Related questions
Question

For a typical cell that is 100 times more permeable to K* than to any other ion, use the Goldman
equation to determine the potential change that would be produced by a doubling of the
extracellular K+ concentration. (Use appropriate concentrations from the previous question).
HINTS: Use 58 in the Goldman equation for results in mV or 0.058 for results in V. Because this
problem is about change (one value relative to another), you do not need to know the
permeabilities of individual ions; you only need to know that PK is 100 times higher than PNa
and PCI.
Be careful how to handle [CI] because of its negative charge.
Transcribed Image Text:For a typical cell that is 100 times more permeable to K* than to any other ion, use the Goldman equation to determine the potential change that would be produced by a doubling of the extracellular K+ concentration. (Use appropriate concentrations from the previous question). HINTS: Use 58 in the Goldman equation for results in mV or 0.058 for results in V. Because this problem is about change (one value relative to another), you do not need to know the permeabilities of individual ions; you only need to know that PK is 100 times higher than PNa and PCI. Be careful how to handle [CI] because of its negative charge.
Expert Solution
steps

Step by step

Solved in 2 steps

Blurred answer
Knowledge Booster
Membrane chemistry
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Human Physiology: From Cells to Systems (MindTap …
Human Physiology: From Cells to Systems (MindTap …
Biology
ISBN:
9781285866932
Author:
Lauralee Sherwood
Publisher:
Cengage Learning