Characterize the differences between tumor cells and normal cells in terms of the following properties. In cancer cells, how might each of these properties contribute to tumor progression? a) contact inhibition b) autocrine stimulation c) apoptosis d) senescence due to telomere shortening e) genomic stability f) angiogenises g) metastasis

Q: What is the fundamental molecular difference that distinguishes a stem cell?

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Q: What is tumor ? Explain the types of tumor a human can face ?

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Q: hallmarks of tumor cells

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Q: What are the normal functions of the BRCA1 tumor suppressor gene?

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Q: Which of the following demonstrates the link between oncogenes and cancer?   a.Oncogenes do not have…

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Q: Which important characteristic of tumor cells did Otto Warburg discover?

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Q: How interfered regulatory machinery results in production of tumor?

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Q: Tumor Suppressor Genes are often called as gatekeepers because: a. They signify their involvement…

A: The correct option is a i.e.They signify their involvement in governing the dynamics of cell…

Q: Name the six fundamental properties of malignant tumours. Which of these properties are amenable to…

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Q: Describe the genetic changes that inactivate tumor-suppressor genes.

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Q: Explain why IC3 is able to stop cancerous cells from dividing ?

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Q: What is the difference between an oncogene and a tumor-suppressorgene? Give two examples of each…

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Q: What is a method some tumors use to evade restriction of their growth by secreting substances that…

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Q: What is required to enable a cancercell to metastasize?

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Q: Which of the following demonstrates the link between oncogenes and cancer?

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Q: Why does ionizing radiation stop cell division?

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Q: What is the role of the microenvironment in cancer development and progression?

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Q: 31. Human cancer cell lines can be implanted into immunocompromised host mice in order to form…

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Q: What would be the effect of a mutation that inactivates the p14ARF tumor suppressor upon p53…

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Q: Is Epithelial-Mesenchymal Transition (EMT) responsible for invasion and/or metastasis of tumors?…

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Q: Which of the following repair mechanisms removes damaged bases in non-dividing cells?

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Q: Which type of mutation would NOT be involved in the inactivation of a tumor suppressor gene?

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Q: How does the epithelial-to-mesenchymal transition (EMT) contribute to tumorigenesis and disease…

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Q: How are cells in a biopsy specimen from a tumoridentified as malignant?

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Q: Explain the following figure. According to this model, what are the two major phases of metastasis…

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Q: What types of evidence indicate that cancer arises from genetic changes?

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Q: Which of the following statements correctly describes a characteristic of tumor-suppressor gene? a)…

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Q: Why is apoptosis preferable to necrosis?

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Q: n of tu

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Q: Why are oncogenes usually dominant in their action, whereas tumor-suppressor genes are recessive?

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Q: Is PI3K a proto-oncogene or a tumor suppressor gene? Why

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Q: Why does a single mutation in a proto-oncogene, turning it into an oncogene potentially lead to a…

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Q: How do we know that malignant tumors arise from a single cell that contains mutations?

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Q: Why is apoptosis significant?

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Q: In DNA repair, how does the normal allele of BRCA1 work? Is it an oncogene or a tumor suppressor…

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Q: What is haploinsufficiency? How might it affect cancer risk?

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Q: What are the key steps of transformation, tumorigenesis and metastasis on a cellular and tissue…

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