Chlorpropamidé håš a lohger NH NHCH,CH,CH,CH, NH NHCH CH,CH,CH, Tobutamide Chlorpropamide Which of the following structures is the most likely metabolite of tolbutamide? HN. NHCH,CHCHCH, NH NHCH CH,CH,CH, HO

Chlorpropamidé håš a lohger NH NHCH,CH,CH,CH, NH NHCH CH,CH,CH, Tobutamide Chlorpropamide Which of the following structures is the most likely metabolite of tolbutamide? HN. NHCH,CHCHCH, NH NHCH CH,CH,CH, HO

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter24: Amines And Heterocycles

Section24.6: Synthesis Of Amines

Problem 8P

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Question

100%

Chlorpropamide has a longer antibiotic activity than tolbutamide.
NHCH,CH,CH,CH3
NH
NHCH CH,CH,CH,
HC
Tobutamide
Chlorpropamide
Which of the following structures is the most likely metabolite of
tolbutamide?
NH
NHCH,CH,CH,CH,
NH
NHCH,CH CH CH,
HOC
HO
NHCH CH,CH,CH,
HN.
NHCH,CH,CH,CO,H
D.
CA
D
B.

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