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Choose (+) if the following circumstances or situations will most likely result to production of intrinsic activity, if otherwise, choose (-). Dissociation of drug molecule from binding site

Choose (+) if the following circumstances or situations will most likely result to production of intrinsic activity, if otherwise, choose (-). Dissociation of drug molecule from binding site

Biochemistry
Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter32: The Reception And Transmission Of Extracellular Information
Section: Chapter Questions
Problem 22P
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Choose (+) if the following circumstances or situations will most likely result to production of intrinsic activity; if otherwise, choose (-)

Choose (+) if the following circumstances or situations will most likely result to production of intrinsic activity; if otherwise, choose (-). + Dissociation of drug molecule from binding site Formation of H-bonds between drug and receptor Presence of hydrophobic interactions Introduction of an antagonist at receptor sites High concentration of competitive antagonist at the binding site Blockade of binding site due to steric hindrance Complementing shapes of drug and binding site Lack of affinity between drug and binding site Formation of an irreversible drug-receptor complex Conformational change between drug and receptor after binding
Transcribed Image Text:Choose (+) if the following circumstances or situations will most likely result to production of intrinsic activity; if otherwise, choose (-). + Dissociation of drug molecule from binding site Formation of H-bonds between drug and receptor Presence of hydrophobic interactions Introduction of an antagonist at receptor sites High concentration of competitive antagonist at the binding site Blockade of binding site due to steric hindrance Complementing shapes of drug and binding site Lack of affinity between drug and binding site Formation of an irreversible drug-receptor complex Conformational change between drug and receptor after binding
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