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Constructing and Using a Pedigree Duchenne's muscular dystrophy (DMD) is a well known, lethal condition, It is a severe linked form of muscular dystrophy characterized by rapid progression of muscle degeneration leading to loss of ambulation and death. This affliction affects one in 3500 males, making it th prevalent of muscular dystrophies, In general, only males are afflicted, though females can be Females may be afflicted if the father is afflicted and the mother is also a carrier or affecte Symptoms usually appear in male children before age 5 and may be visible in early infancy. Muscle weakness of the legs and pelvis spreads to the arms, neck, and other areas. By braces may be required to aid in walking but most patients are wheelchair dependent by age 1. progressive deterioration of muscle, loss of movement occurs eventually leading to paralysis. life expectancy for patients afflicted with DMD varies from late teens to early to mid 20s. K this disease is inherited through family members nyspected of carrying the allele will be help counseling and decision making. Procedure 1, Consider the following information gathered from four generations of a family: Two people marry and have four children (F1) in the following order: dau daughter, and daughter The first daughter (F,) marries and has three children: a son, a daught daughter. Her first daughter does not marry, The second daughter ma produces a son, who develops DMD, and two daughters. The son (F,) develops DMD and dies The second daughter (F) marries, but produces no children The third daughter (F.) marries and has two children: a son who devela and dies, anda second son. Her second son marries. His wife producesc and then a son.

Constructing and Using a Pedigree Duchenne's muscular dystrophy (DMD) is a well known, lethal condition, It is a severe linked form of muscular dystrophy characterized by rapid progression of muscle degeneration leading to loss of ambulation and death. This affliction affects one in 3500 males, making it th prevalent of muscular dystrophies, In general, only males are afflicted, though females can be Females may be afflicted if the father is afflicted and the mother is also a carrier or affecte Symptoms usually appear in male children before age 5 and may be visible in early infancy. Muscle weakness of the legs and pelvis spreads to the arms, neck, and other areas. By braces may be required to aid in walking but most patients are wheelchair dependent by age 1. progressive deterioration of muscle, loss of movement occurs eventually leading to paralysis. life expectancy for patients afflicted with DMD varies from late teens to early to mid 20s. K this disease is inherited through family members nyspected of carrying the allele will be help counseling and decision making. Procedure 1, Consider the following information gathered from four generations of a family: Two people marry and have four children (F1) in the following order: dau daughter, and daughter The first daughter (F,) marries and has three children: a son, a daught daughter. Her first daughter does not marry, The second daughter ma produces a son, who develops DMD, and two daughters. The son (F,) develops DMD and dies The second daughter (F) marries, but produces no children The third daughter (F.) marries and has two children: a son who devela and dies, anda second son. Her second son marries. His wife producesc and then a son.

Human Heredity: Principles and Issues (MindTap Course List)
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter10: From Proteins To Phenotypes
Section: Chapter Questions
Problem 3CS: A couple was referred for genetic counseling because they wanted to know the chances of having a...
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So the question is asking to construct a pedigree, but I am extremely confused on how to find the genotypes of the sons and daughters. The trait is x-linked recessive.
Constructing and Using a Pedigree Duchenne's muscular dystrophy (DMD) is a well known, lethal condition, It is a severe recessive X- linked form of muscular dystrophy characterized by rapid progression of muscle degeneration, eventually leading to loss of ambulation and death. This affliction affects one in 3500 males, making it the most prevalent of muscular dystrophies, In general, only males are afflicted, though females can be carriers, Females may be afflicted if the father is afflicted and the mother is also a carrier or affected. Symptoms usually appear in male children before age 5 and may be visible in early infancy. Muscle weakness of the legs and pelvis spreads to the arms, neck, and other areas. By age 10, braces may be required to aid in walking but most patients are wheelchair dependent by age 12, Due to progressive deterioration of muscle, loss of movement occurs eventually leading to paralysis. The average life expectancy for patients afflicted with DMD varies from late teens to early to mid 20s. Knowing how this disease is inherited through family members yspected of carrying the allele will be helpful in genetic counseling and decision making. Procedure 1. Consider the following information gathered from four generations of a family: Two people marry and have four children (F)) in the following order: daughter, son, daughter, and daughter The first daughter (F,) marries and has three children: a son, a daughter, another daughter, Her first daughter does not marry, The second daughter marries and produces a son, who develops DMD, and two daughters. The son (F,) develops DMD and dies The second daughter (F) marries, but produces no children The third daughter (F,) marries and has two children: a son who develops DMD and dies, anda second son Her second son marries. His wife produces a daughter and then a son. 2. Construct a pedigree chart to represent the family history given,
Transcribed Image Text:Constructing and Using a Pedigree Duchenne's muscular dystrophy (DMD) is a well known, lethal condition, It is a severe recessive X- linked form of muscular dystrophy characterized by rapid progression of muscle degeneration, eventually leading to loss of ambulation and death. This affliction affects one in 3500 males, making it the most prevalent of muscular dystrophies, In general, only males are afflicted, though females can be carriers, Females may be afflicted if the father is afflicted and the mother is also a carrier or affected. Symptoms usually appear in male children before age 5 and may be visible in early infancy. Muscle weakness of the legs and pelvis spreads to the arms, neck, and other areas. By age 10, braces may be required to aid in walking but most patients are wheelchair dependent by age 12, Due to progressive deterioration of muscle, loss of movement occurs eventually leading to paralysis. The average life expectancy for patients afflicted with DMD varies from late teens to early to mid 20s. Knowing how this disease is inherited through family members yspected of carrying the allele will be helpful in genetic counseling and decision making. Procedure 1. Consider the following information gathered from four generations of a family: Two people marry and have four children (F)) in the following order: daughter, son, daughter, and daughter The first daughter (F,) marries and has three children: a son, a daughter, another daughter, Her first daughter does not marry, The second daughter marries and produces a son, who develops DMD, and two daughters. The son (F,) develops DMD and dies The second daughter (F) marries, but produces no children The third daughter (F,) marries and has two children: a son who develops DMD and dies, anda second son Her second son marries. His wife produces a daughter and then a son. 2. Construct a pedigree chart to represent the family history given,
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