Control - Rat liver Suspected mutagen Rat liver extract extract Salmonella- strain (requires histidine) -Salmonella strain (requires histidine) Plate the mixtures onto petri plates that lack histidine. Incubate overnight to allow bacterial growth. A large number of colonies suggests that the suspected mutagen causes mutation. FIGURE 19.15 The Ames test for mutagenicity.

Biology 2e
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Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark
Chapter14: Dna Structure And Function
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Problem 37CTQ: An adult with a history of tanning has his genome sequenced. The beginning of a protein-coding...
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What is the purpose of the rat liver extract in this procedure?

Control
- Rat liver
Suspected
mutagen
Rat liver
extract
extract
Salmonella-
strain
(requires
histidine)
-Salmonella
strain
(requires
histidine)
Plate the mixtures onto petri
plates that lack histidine.
Incubate overnight to
allow bacterial growth.
A large number of colonies
suggests that the suspected
mutagen causes mutation.
FIGURE 19.15 The Ames test for mutagenicity.
Transcribed Image Text:Control - Rat liver Suspected mutagen Rat liver extract extract Salmonella- strain (requires histidine) -Salmonella strain (requires histidine) Plate the mixtures onto petri plates that lack histidine. Incubate overnight to allow bacterial growth. A large number of colonies suggests that the suspected mutagen causes mutation. FIGURE 19.15 The Ames test for mutagenicity.
Expert Solution
Step 1

Mutations refer to the random changes in the genome of the organisms. 

Step 2

The chemicals or any other substances that can induce mutations are called mutants.

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