1. Copemnan et al. (1995) examined 21 microsatellite marker loci in 445 human familieswith type 1 diabetes (T1D). One marker locus, D2S152, had three alleles (denote I, II, II)that are candidate to have a significant effect on T1D. The following table provides thedata for these three alleles. For example, parents heterozygous for marker D2S152transmitted allele I to T1D offspring 81 times while transmitting an alternative alleleonly 45 times. What are the likelihood ratio, LOD score, and P-value under TDT?Multiple testing should be considered. What conclusion can be drawn about the markerlocus D2S152?AlleleTransmittedNot transmitted8145II5973II3624

Answered: Copemnan et al. (1995) examined 21…

MATLAB: An Introduction with Applications

6th Edition

ISBN:9781119256830

Author:Amos Gilat

Publisher:Amos Gilat

Chapter1: Starting With Matlab

Section: Chapter Questions

Problem 1P

See similar textbooks

Similar questions

The article “Effects of Diets with Whole Plant-Origin Proteins Added with Different Ratiosof Taurine:Methionine on the Growth, Macrophage Activity and Antioxidant Capacity ofRainbow Trout (Oncorhynchus mykiss) Fingerlings” (O. Hernandez, L. Hernandez, et al.,Veterinary and Animal Science, 2017:4-9) reports that a sample of 210 juvenile rainbowtrout fed a diet fortified with equal amounts of the amino acids taurine and methionine for aperiod of 70 days had a mean weight gain of 313 percent with a standard deviation of 25, while 210 fish fed with a control diet had a mean weight gain of 233 percent with a standard deviation of 19. Units are percent. Find a 99% confidence interval for the difference in weight gain on the two diets.
Suppose a researcher is interested inthe effectiveness in a new childhood exercise program implemented in a SRS of schools across a particular county. In order to test the hypothesis that the new program decreases BMI (Kg/m2), the researcher takes a SRS of children from schools where the program is employed and a SRS from schools that do not employ the program and compares the results. Assume the following table represents the SRSs of students and their BMIs. Student intervention group BMI (kg/m2) Student control group BMI (kg/m2) A 18.6 A 21.6 B 18.2 B 18.9 C 19.5 C 19.4 D 18.9 D 22.6 E 24.1 F 23.6 A) Assuming that all the necessary conditions are met (normality, independence, etc.) carry out the appropriate statistical test to determine if the new exercise program is effective. Use an alpha level of 0.05. Do not assume equal variances.B) Construct a 95% confidence interval about your estimate for the average difference in BMI between the groups.
A researcher conducted a medical study to investigate whether taking a low-dose aspirin reduces the chance of developing colon cancer. As part of the study, 1,000 adult volunteers were randomly assigned to one of two groups. Half of the volunteers were assigned to the experimental group that took a low-dose aspirin each day, and the other half were assigned to the control group that took a placebo each day. At the end of six years, 15 of the people who took the low-dose aspirin had developed colon cancer and 26 of the people who took the placebo had developed colon cancer. At the significance level α = 0.05, do the data provide convincing statistical evidence that taking a low-dose aspirin each day would reduce the chance of developing colon cancer among all people similar to the volunteers?
A researcher was interested in studying if there is a significant relationship between the severity of COVID 19 and blood types of individuals. 2400 individuals were studied and the results are shown below. Condition Blood Type O A B AB Total Critical 64 44 20 8 136 Severe 175 129 50 15 369 Moderate 211 528 151 125 1015 Mild 200 400 140 140 880 Total 650 1101 361 288 2400 State both the null and alternative, Provide the decision rule for making this Use an alpha level of 5%, Show all of the work necessary to calculate the appropriate, What conclusion are you allowed to draw? Would your conclusion change at the 10% level of significance?
A sample of men and women who had passed their driver's test either the first time or the second time were surveyed, with the following results: Results of the driving testGender First time Second timeMen 126 211Women 135 178a) Do these data suggest that there is a relationship between gender and the passing of their driver’s test from which the present sample was drawn? Let alpha=.05
A research on the effect of duodenal infusion of donor feces for recurrent Clostridium difficile examined patients with C. difficile infections which cause persistent diarrhea. Some patients were given the antibiotic vancomycin, while others were given a fecal transplant. At alpha = 0.01, test if the result is dependent on the type of treatment given.
A psychologist at a private mental hospital was asked to determine whether there was a clear difference in the length of stay for patients with different categories of diagnosis. Looking at the last four patients in each of the three major categories, the results (in terms of weeks of stay) were as follows: Diagnosis Category Affective Disorders Cognitive Disorders Drug-Related Conditions 7 12 8 6 8 10 5 9 12 6 11 10 Using alpha = 0.05, is there a significant difference in length of stay among diagnosis categories? Show all five steps of hypothesis testing. For additional practice, compute the means and standard deviations for each group. What is the purpose of a post hoc test? What does it tell us? Explain why we do not need a post hoc test if there are only two groups in our study. Conduct Tukey's HSD post hoc test to determine where there is a difference in the three groups.
A psychologist at a private mental hospital was asked to determine whether there was a clear difference in the length of stay for patients with different categories of diagnosis. Looking at the last four patients in each of the three major categories, the results (in terms of weeks of stay) were as follows: Diagnosis Category Affective Disorders Cognitive Disorders Drug-Related Conditions 7 12 8 6 8 10 5 9 12 6 11 10 Using alpha = 0.05, is there a significant difference in length of stay among diagnosis categories? Show all five steps of hypothesis testing and compute the means and standard deviations for each group.
A District manager kept track of the sales of 14 stores before the start of an advertisement campaign and after the sales campaign. Check for significant gains in sales at the 0.05 alpha level. State the hypothesis that you are checking. Summarize your results. Store number Daily sales: Pre-sales campaign Daily sales: Post-sales campaign 1 $10,000 $7,000 2 $9,000 $7,500 3 $8,500 $8,000 4 $8,000 $8,500 5 $9,000 $8,500 6 $10,000 $7,500 7 $9,000 $8,000 8 $8,000 $8,500 9 $8,500 $9,000 10 $9,000 $9,500 11 $11,000 $10,000 12 $10,000 $11,000 13 $8,000 $11,500 14 $7,000 $12,000
. A new chemotherapy drug is released to treat leukemia and researchers suspect that the drug may have fewer side effects than the most commonly used drug to treat leukemia. The two drugs have equivalent efficacy. In order to determine if a larger study should be conducted to look into the prevalence of side effects for the two drugs, set up a Mann-Whitney U test at the alpha equals .05 level and interpret its results. Number of Reported Side-EffectsOld Drug 0 1 1 3 5New Drug 0 0 1 2 4 Old Drug New Drug Total Sample(Ordered Smallest to Largest) RanksOld Drug New Drug Old Drug New DrugR1= R2= A) We reject H0 in favor of H1, which states the two populations are not equal at the alpha equals .05 level because the calculated U value of 10 is greater than the critical U value of 2.B) We reject H0 in favor of H1, which states the two populations are not equal at the alpha equals .05 level because the calculated U value of 8.5 is greater than the critical U value of 2.C) We fail to reject H0,…
In 1992, the U.S. Public Health Service and the Centres for Disease Control and Prevention recommended that all women of childbearing age consume 400mg of folic acid daily to reduce the risk of having a pregnancy that is affected by a neural tube defect such as spina bifida or anencephaly. In a study by Stepanuk et al. (A-3), 693 pregnant women called a teratology information service about their use of folic acid supplementation. The researchers wished to determine if preconceptional use of folic acid and race are independent. The data appear in Table below: Total Preconceptional Use of Folic Acid Race No Yes 559 299 260 White 56 41 15 Black 21 14 7 Other 636 354 282 Total Test the hypothesis that there is no association between the usage of folic acid and race with 5% significant level and using SPSS (Choose only 4 correct answers from the following statements): 1. The null and alternative hypothesis are: H0: The two variables are dependent. H1: The two…
A study was performed on 200 elementary school students to investigate whether regular Vitamin A supplementation was effective in preventing colds during the month of March. 100 were randomized to receive daily Vitamin A supplements during the month of March, and 100 students were randomized to a placebo group (and did not receive Vitamin A) during the same month. The number of students getting at least one cold in March was computed in the two groups, and the results are given in the following 2 X 2 table. Using a 5% level of significance determine whether there is an association between Vitamin A supplementation and prevention of Common Cold ColdNo Cold Vitamin A1585100 Placebo2575100 40160200

SEE MORE QUESTIONS

Recommended textbooks for you

MATLAB: An Introduction with Applications

Statistics

ISBN:

9781119256830

Author:

Amos Gilat

Publisher:

John Wiley & Sons Inc

Probability and Statistics for Engineering and th…

Statistics

ISBN:

9781305251809

Author:

Jay L. Devore

Publisher:

Cengage Learning

Statistics for The Behavioral Sciences (MindTap C…

Statistics

ISBN:

9781305504912

Author:

Frederick J Gravetter, Larry B. Wallnau

Publisher:

Cengage Learning

MATLAB: An Introduction with Applications

Statistics

ISBN:

9781119256830

Author:

Amos Gilat

Publisher:

John Wiley & Sons Inc

Probability and Statistics for Engineering and th…

Statistics

ISBN:

9781305251809

Author:

Jay L. Devore

Publisher:

Cengage Learning

Statistics for The Behavioral Sciences (MindTap C…

Statistics

ISBN:

9781305504912

Author:

Frederick J Gravetter, Larry B. Wallnau

Publisher:

Cengage Learning

Elementary Statistics: Picturing the World (7th E…

Statistics

ISBN:

9780134683416

Author:

Ron Larson, Betsy Farber

Publisher:

PEARSON

The Basic Practice of Statistics

Statistics

ISBN:

9781319042578

Author:

David S. Moore, William I. Notz, Michael A. Fligner

Publisher:

W. H. Freeman

Introduction to the Practice of Statistics

Statistics

ISBN:

9781319013387

Author:

David S. Moore, George P. McCabe, Bruce A. Craig

Publisher:

W. H. Freeman

SEE MORE TEXTBOOKS