Q: Describe the influence of protein binding on drug bioavailability
A: The extent to which drugs bind to proteins in the blood or tissue is referred to as protein binding.…
Q: Analyze the list of combinations per item and identify the type of therapeutic incompatibility. In…
A: Biotin + thyroxine - E ( gives a false lab result ) Atropine + phenobarbital - H ( intentional…
Q: Explain why body fluids pH can affect drug absorption and distribution.
A: pH can be defined as the negative logarithm of hydrogen ions. Normal pH scale is between acidic to…
Q: Proteases belong to the 'lyases' group of enzymes: O a. FALSE O b. TRUE
A: Lysases are enzymes that catalyzes the breaking of C-C, C-O, C-N, C-S and other bonds by means…
Q: 1.The discovery step and the identification or consisting of the choice of the therapeutic target…
A: A therapeutic target or biological target is anything inside a living organism that can be targeted…
Q: For biotech products (i.e. insulin, growth hormones), explain and illustrate the importance of…
A: Protein purification is the process by which the desired protein is isolated from a sample mixture.…
Q: TH increased bioavailability of drugs
A: Bioavailability of drug is defined as the amount or concentration of the drug that is absorbed/…
Q: Define therapeutic index and explain its importance.
A: Therapeutic Index is also known as Therapeutic Ratio. It is a quantitative measurement of the…
Q: Describe the different types of trials a new drug must undergo before it is “ready for market.”
A: A drug is a chemical substance that produces a biological effect. When the drug is taken by…
Q: 78. Which situation(s) might result in a higher than expected plasma drug concentration? a. Enzyme…
A: The volume of distribution (vd) of a drug describes the total amount of a drug and the plasma…
Q: Amoxicillin is a commonly used drug to fight bacteria. The pharmacologic class of this drug is: A.…
A: A:- Amino- penicillin-beta- lactamase inhibitors
Q: definition of PBS (pharmaceutical benefit scheme)
A: Pharmaceutical benefit scheme This scheme subsides the prescribed medicine cost and makes those…
Q: MAtch these drugs according to their functions below Cell wall synthesis inhibitors 50s Ribosomal…
A: Introduction Antibiotics are antimicrobial substances that are active against bacteria. Antibiotic…
Q: Discuss the effects of glass packaging materials on pharmaceutical dosage form? Discuss at your own…
A: Packaging refers to the process of wrapping or safeguarding products in preparation for delivery,…
Q: Explain the phenomenon of drug resistance from the standpoint ofmicrobial genetics (include a…
A: Microbes such as bacteria, fungi, protozoa, and viruses, etc, provide a relatively simple system for…
Q: ase give point on
A: Drugs are any substances when taken into the body bring out psychological and physiological changes…
Q: What is the significance of pl herapeutic activity of a drug?
A: The plasma level time curve is the graph plotted after measuring the plasma drug concentration at…
Q: discuss how particle size affecting drug absorption ?
A: The quality of a drug depends on a number of factors. The dissolution rate of a drug plays a major…
Q: Describe the influence of protein binding on drug bioavailability
A: Protein binding is the extent to which drugs can bind to proteins in the blood or tissues. The…
Q: Describe the five basic mechanisms of drug resistance.
A: Antibiotics are the drugs which are used to kill the pathogenic bacteria. Penicillin is the first…
Q: The best way to make human protein for drug use is to
A: Proteins are the key factors of most all the functions of a cell. Any impairment in the production…
Q: List all the possible modes of entry of the drug to the target cell membranes.
A: There are different ways of entry of drugs to the target cell membrane. The most important ones are…
Q: Explain mechanisms of drug toxicity? How various strategies are used to treat the drug toxicity and…
A: Drug toxicity can be outlined as the toxicity which occurs because of ingesting more drugs that are…
Q: Q/What are the Irreversible inhibitor ?
A: Inhibitor is an agent that slows or interferes with the chemical reaction. Enzyme inhibitor is a…
Q: Describe the Mechanisms of Drug Resistance with an example.
A: Resistance is improvement of the capacity to withstand the beforehand dangerous impact of a drug by…
Q: Explain the differences between in-vitro and in-vivo testing of Pharmaceutical products. Give…
A: One of the primary goals in the pharmaceutical development of the dosage in oral forms can be…
Q: Explain the uses of the minimum inhibitory concentration and thetherapeutic index in drug selection.
A: Microbes that cause diseases are called pathogens.
Q: Identify the binding interactions that might be possible for the drug reported below. Rank these…
A: The possible interaction of the drug binding can be -Negative interaction with the amino acid…
Q: Identify the criteria the compounds must meet in order to be developed into drugs.
A: A pharmaceutical drug or medicine is a compound that is used either for the diagnosis, treatment,…
Q: Identify the classification of drug metabolism and specific type of reaction involved in each drug…
A: Drug metabolism is a metabolic drug breakdown by living organisms often through special enzymatic…
Q: Please choose all the ADVANTAGES of protein-based drugs such as antibodies compare to small…
A: When ingested into a living system, drugs are any chemical compounds that affect/alter the…
Q: How could the manufacturing process affect drug product performance
A: The performance of the drug is based on factors such as the dissolution of the drug, the time of the…
Q: Describe some Specific Drugs and Their Metabolic Targets. Give some uses.
A: Drug metabolism is a term used to describe the biotransformation of drugs in the body for easy…
Q: Give two examples of macromolecules that are chosen as drug targets. What are antiseptics? Give an…
A: Macromolecules are the molecules having large molecular mass. These are mostly polymers.
Q: Indicate whether each statement is true or false, and justify your answer.Phase III clinical trials…
A: Clinical trials are usually conducted in phases that build on one another. Each phase is designed to…
Q: ne the importance of dietary supplements, including their active agent, and to know if it is…
A: A healthy diet contains various essential dietary minerals which include calcium, phosphorus,…
Q: Explain how drugs may interact with nucleic acids as a drug target, and outline how a medicinal…
A: Drugs are used to treat a disease. The disease is caused when there is a deviation from the normal.…
Q: a. What is a drug target? Why is it important to identify a drug target to treat a disease?
A: A drug is a molecule which might resemble a organic molecule inside the body or an exogenous…
Q: Most commonly available Non-prescription Proton Pump Inhibitor (PPI) medications: Name of the Drug…
A: The proton pump inhibitor are used to treat the stomach acid production. This works by blocking the…
Q: Enzyme activity can be inhibited by inhibitors. Inhibitors can be bio-molecules or chemically…
A: An enzyme is a biocatalyst that increases the rate of chemical reaction without itself being changed…
Q: Describe three situations where you would use an excipient in your drug formulation and how you…
A: Excipients can be outlined as inert substances that are utilized in the drugs as diluents.…
Q: Explain chemotherapy in terms of specific inhibitionCompetitive Inhibition,Noncompetitive…
A: Cancer: A disease condition in which there is abnormal growth of the cells occurs and results in the…
Q: Define the concept of drug bioavailability and briefly explain how it is experimentally determined.…
A: bio-availability of a drug is the indicator or measure to check how much the administered dosage of…
discuss the chemotherapy in terms of enzymes activities
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Solved in 4 steps
- Identify the classification of drug metabolism and specific type of reaction involved in each drugsample. Identify the enzyme involved in each reaction. Identify the classification of drug metabolism and specific type of reaction involved in each drugsample. Identify the enzyme involved in each reaction.What are the various structures of drug regulation? Please answer at your own easy words. Answer should be to the point.
- Match these drugs with the following functions Cell wall synthesis inhibitors 50s Ribosomal subunit inhibitors Anti-metabolite Cell Membrane disrupters DNA synthesis inhibitor 30s Ribosomal subunit inhibitorsGive an example of N-dealkylation and oxidative deamination over the active molecule of a drug and indicate which type of metabolization they are.Match these drugs from these functions Cell wall synthesis inhibitors 50s Ribosomal subunit inhibitors Anti-metabolite Cell Membrane disrupters DNA synthesis inhibitor 30s Ribosomal subunit inhibitors
- State and describe the three different types of inhibitors. short answer please.What is meant by the rate-limiting step in drug bioavailability from a solid oral drug product? This under Bipharmaceurics and Pharmacokinetics subjectState the principle that underlies the following biochemical tests: a. Voges-Proskauer test