) Discuss the transition state(s) in reaction coordinate diagram in the context of ΔG. 2) If an enzyme deceases the activation energy, ΔG‡, by the quantity X, we learned that the forward rate constant is increased by multiplication with the factor eX/RT. Why does this simple fact demonstrate that small changes in activation energy give big changes in catalyzed rates?   7)Two people study the same enzyme. They get different Vmax in each experiment, but the same kcat. Why?

Q: 2. A reaction was found to proceed mechanistically in two steps. The following data was reported:…

A: Given:  Step 1:  Eact = 35 KJ/mol  ∆H° = +25KJ/mol  Step 2 :  Eact = 7 KJ/mole  ∆H° = -45 KJ/mol

Q: An enzyme has a Km equal to 1.0 x 10-4 M (molar) for a certain substrate S. When [S] = 1.0 x 10-4 M,…

A: Km = 1.0 x 10-4 M [S] = 1.0 x 10-4 M     Vo = Vmax[S]/{Km + [S]} At Km = [S] Vo = Vmax/2   (a) and…

Q: The following results were obtained for the action of an ATPase on ATP at 20 oC. when the…

A: Given: The given values are, The concentration of ATPase is E0  = 20 nmol dm-3

Q: 2. Which of the following kinds of catalysis can be explained by the adsorption theory? A. enzyme…

A: 2. The theory of heterogeneous catalysis states that the reactants in the gaseous or solution phases…

Q: What is rate constant 1

A: Given :- half life (t1/2) = 5730 years To calculate :- rate constant (in years-1)

Q: The enzyme urease increases the rate of urea hydrolysis at pH 8.0pH 8.0 and 20 °C20 °C by a factor…

A: Given, pH of urea = 8.0 Rate enhancement factor = =1014 Time = 88 min T=20°C

Q: Temperature effect on the degradation of a multisulfa preparation was evaluated at 60 and 70°C. If…

A: given, at temperature, T1 = 60°C = (60+273)K = 333K at temperature, T2 =  70°C = (273+70)K = 343K…

Q: In the following reaction, a molecule of ATP bound to the enzyme transfer a phosphate to fructose…

A:

Q: VII.  A possible reaction for the degradation of the pesticide DDT to a less harmful compound was…

A:

Q: nzyme is added to a solution (1.0 mL) containing its substrate at a concentration of 100 times the…

A:

Q: How many kJ/mol must an enzyme lower the activation energy of the reaction to make it useful? We…

A: The lowest energy by which the reacting molecules gets energized to create the final product is…

Q: For the attachment of a substrate to the active site of an enzyme: k1 S+E→ SE k-1 The equilibrium…

A: A unitless number relating both direction rates (forward and backward) of any equilibrium reaction…

Q: r an enzyme that displays Michaelis-Menton kinetics, what is the reaction velocity, V (as a…

A:

Q: Which one of the following is true regarding our coverage of enzyme kinetics? Increasing the…

A: Fourth option is correct.

Q: For enzymatic reaction, a mechanism was proposed by Michaelis and Menten as follows: E  +  S  ↔ ES;…

A: An enzyme solution has a fixed number of active sites to which substrates can bind. At high…

Q: The hydrolysis of a substrate, S, by an enzyme has been studied in the lab. The following initial…

A: Consider the reaction where a substrate 'S' is converted to its product 'P' by an enzyme. The rate…

Q: 1. A liquid medicine having an initial drug concentration of 1000 mg/mL undergoes zero-order…

A: 1) Solution - According to the question - Given - It is a zero order reaction. Initial concentration…

Q: Temperature effect on the degradation of a multisulfa preparation was evaluated at 60 and 70 C. If…

A:

Q: Since changing the environment of the spill is not possible, you need other ways to speed up oil…

A: Since the relationship between the rate constant and activation energy is given as  Hence we can…

Q: The enzyme carbonic anhydrase catalyzes the following reaction: CO2 (g) + H2O(1) + HCO3-(aq) + H+…

A:

Q: 3. Carbonic anhydrase has two substrates, carbon dioxide and bicarbonate, which are both converted…

A: CO2 would act as a noncometitive inhibitor. Because Non-competitive inhibition is a type of enzyme…

Q: Sketch the reaction profile for a reaction having Ea = 50 kJ/mol and (change in)Hrxn = -75 kJ/mol.…

A: For the given reaction,drawn in the picture is the energy profle diagramThe uncatalyzed reaction is…

Q: For the following reaction catalysed by an enzyme E k1 E + S = ES k-1 E + P • describe the meaning…

A: Since you have posted a question with multiple sub-parts, we will solve first three subparts for…

Q: By what factor is the rate of a reaction changed if an enzyme lowers the Ea by 6.0 kJ/mol at 37°C?

A: Given:  Temp = 37°C = 310K. Ka= 6KJ/mol Now using Arrhenius Eqn:   ln (K)= Ea/RT  Ea = ln(K) RT  Ea…

Q: 25. A student measures the following initial rate data for an enzyme that obeys Michaelis- Menten…

A: As the enzyme obeys Michaelis-Menten kinetics, so the plot of 1/[V0] vs 1/[S] would be linear. From…

Q: 10.38. The following data relate to an enzyme reaction. 10³[S]/mol dm³ 105 V/mol dm³ s-1 2.0 13 4.0…

A:

Q: 2.2 Suppose that the following sequence describes the reactions of two different substrates…

A: solution               Find the rate of equation by making the Michaelis - Menten assumption = ?

Q: An enzyme catalyzes the reaction A ⇌ B. The enzyme is present at a concentration of 2 nM, and the…

A: Given information: Vmax is 1.2 μM s −1 Km = 10 μM

Q: The enzyme-catalyzed conversion of a substrate has a Michaelis constant of 0.032 mole dm-3. The rate…

A:

Q: Arrhenius Equation The variation of the rate constant with temperature can be expressed by the…

A:

Q: The uncoiling of deoxyribonucleic acid (DNA) is a first-order reaction. Its activation energy is 420…

A:

Q: For enzyme-catalyzed reactions that follow the mechanism E +S= E· S E·S= E+P a graph of the rate as…

A: The enzyme catalysis reaction is shown as, The first step involves the reaction between enzyme and…

Q: Consider the following enzyme-catalyzed reaction: S - P Which of the following statements are…

A: The Enzyme catalyzed reaction proceeds as: E+S  ⇋k-1k1  ESES  →k2  P+E The rate of this reaction is…

Q: Calculate the ratio of rates of enzyme-catalyzed to non-catalyzed reactions at 37 °C given that the…

A: Rate of reaction represents the change of concentration of a reactant or a product with respect to…

Q: Certain bacteria use the enzyme penicillinase to decom- pose penicillin and render it inactive. The…

A: Given,       Michalis - Menten constants for pencillinase to decompose penicillin  are Km = 5×10-5…

Q: The acid-catalyzed hydrolysis of sucrose occurs by the fol-lowing overall reaction whose kinetic…

A: First order reaction The integrated rate equation for first order reaction is ; k=1tln…

Q: 4. The enzyme, Xase (hypothetical, has the following kinetics: k1 k2 S+E ES + E+P k-1 k1 = 10 ° M1…

A: Michaelis - Menten equation is the equation that relates the rate of enzymatic reactions i.e.…

Q: What chemical reaction is being catalyzed in this experiment? Label the substrate(s), enzyme and…

A: The chemical reaction being catalyzed is the decomposition of hydrogen peroxide (H2O2) by the enzyme…

Q: In a temperature-jump experiment to investigate the kinetics of an isomerization reaction that is…

A: The calculations are as shown below

Q: CO2(g) + H2O(l) → H2CO3(aq) For the carbonic anhydrase activity specified by the equation above,…

A: Given reaction- CO2 (g) + H2O (l) → H2CO3 (aq) To find - Standard reaction Gibbs energy at 25 °C…

Q: An enzyme catalyzes a reaction at a rate of 20 micromolar/min.mg when the concentration of substrate…

A: The Michaelis-Menten equation of an enzyme catalysed reaction is given as:

Q: Aresearcher raises the temperature from 56.8 to 69.6 "C and finds that the rate of the reaction…

A:

Q: Suppose that a certain biologically important reaction is quite slow at physiological temperature…

A: Arrhenius equation is given by,

Q: A research group discovers a new version of happyase, which they call happyase*, that catalyzes the…

A: Answer - According to the question -  the chemical reaction HAPPY ⇌ SAD. a. kcat = Vmax/[Et] = (1.6…

Q: 15. Consider an enzyme that has a kcat that is 1000.0 times larger than kuncat at 15°C. If the…

A: T = 15°C  Or T = 15+273 = 288 K  16.5 KJ/mol enzyme decreases the activation energy for the…

Q: 3. Interpret the graph. (At least 2 sentences) Minimum kinelic energy for catalyzed reaction Minimum…

A: The energy associated with the motion of the particles is commonly termed as the kinetic energy of…

Q: Temperature effect on the degradation of a multisulfa preparation was evaluated at 60 and 70°C. If…

A: We are given two different temperature values and the rate constant values for these temperatures.…

Q: The data in the table below describe an enzymatic reaction. The relative molecular mass of the…

A: Molecular mass of enzyme     = 50000 gmol Concentration of the enzyme = 2 × 10-3 gcm-3