Q: How do most transcription factors determine which genes they act upo
A: Protein synthesis through genes occurs in two steps: The DNA sequence present in the gene is…
Q: If the gene product is protein then why not to provide these protein from exogenous source to meet…
A: DNA undergoes transcription to form RNA which then undergoes translation to form DNA.
Q: Why are some chromosomal regions amplified/deleted in a specific manner in certain tumor types?
A: Chromosomal amplification: Chromosomal amplification can be explained as the increase in the amount…
Q: How do Epigenetics connect to the unifying themes in biology and the crosscutting concepts. (Give 2…
A: Life often involves changes that can affect our gene pool. These changes often arise from the…
Q: Which snRNP leaves in order to form the active spliceosome? OU1 U3 OU4 U2
A: At least five different types of snRNPs join mainly the spliceosome to specifically participate in…
Q: TP53 encodes the p53 tumor suppressor gene and is the most mutated gene in cancer with 50% of…
A: Any abnormality in chromosome structure during G1 phase cell cycle is captured by the protein called…
Q: Discuss the similarities and differences of phenotypic variations that are caused by epigenetic gene…
A: Genetics is a branch of science that deals in the study of genes, heredity, and genetic variation of…
Q: What percentage of the human genome is nowpredicted to have functionality in at least one cell type?
A: The gene is the basic physical and functional unit of heredity. The genome is the genetic material…
Q: The following is true about epigenetic gene control: O epigenetic changes to the chromatin may…
A: Epigenetics is that the study of however your behaviors and surroundings will cause changes that…
Q: Which molecules recognize the TATA box before RNA polymerase binds to the promoter region? Mitotic…
A: The transcription is the process by which RNA is produced from the DNA. In case of prokaryotic cells…
Q: Why is the p53 R273W mutation preventing p53 from binding to DNA?
A: All living things are made up of cells, which are the most basic and important unit. All of life's…
Q: statement is true. Both statements are false. 1. Epigenetics does not consider how exposure to…
A: Epigenetics is the study of how your behaviour and environment can influence how your genes…
Q: How histone and micro RNA controls gene expressi
A: Histones are positively charged basic proteins that associate with DNA in the nucleus and forms…
Q: The molecular mechanisms that underlie epigenetics include which of the following? (select all that…
A: The expression of genes can be controlled by different mechanisms. The epigenetic modification is…
Q: Which of the following are examples of molecular changes thatcan have an epigenetic effect on gene…
A: Epigenetic effects are such changes that bring about changes in the phenotypic expression of a gene…
Q: An hnRNA molecule contains three exons, with the middle one being an “alternative” exon. How many…
A: Splicing is the process in which the introns are removed from the RNA, and the exons are combined to…
Q: What have epigenetic monozygotic twin studies proven? A. Twins have identical epigenomes because…
A: The term epigenetics means something that occurs due to a non-genetic influence on the expression of…
Q: do neutral mutations affect gene expressi
A: Except for some viruses, most animals' genetic material is a double-stranded molecule called DNA. A…
Q: CpG is an epigenetic term which me a. The binding of the sense cy O b. The binding of cytidine to O…
A: CpG site The CpG sites or CG sites are regions of DNA where Cytosine nucleotide is followed by a…
Q: All the cells of one organism share the same genome. However, during development, some cells develop…
A: Developmental biology and stem cell biology helps us to understand more about the fate of cells. The…
Q: x is an epigenetically controlled process where axpression of genes occurs following a parent of…
A: The external modification of DNA without changing the sequence but alters the physical structure…
Q: What is meant by epigenesis? How did Kaspar Friedrich Wolff ’s concept of epigenesis differ from the…
A: Epigenesis is the development of an animal or plants from the egg or spore via the processes in…
Q: Many transposons move within a genome by replicative mechanisms . They therefore increase in copy…
A: Transposon is a type of genetic element that can "jump" to different places in the genome. Although…
Q: Discuss how epigenetic processes can be modified by environmental factors.
A: The study of heritable phenotypic changes without adjustments to DNA sequence is known as…
Q: Often, the physical characteristics of genetically identical twins become increasingly different as…
A: The study of changes in the phenotype of an individual due to environmental factors without changing…
Q: does epigenetics agree or run counter (contradict) to the traditional genetic basis of inheritance…
A: Epigenetics is the study of how genes are expressed, or turned on and off. This can be influenced by…
Q: How can environmental agents that do not cause gene mutationscontribute to cancer? Would these…
A: A gene is a particular sequence of nucleotides in RNA or DNA that is generally located on a…
Q: Explain how two genetically identical twins are not really identical.
A: Identical twins are are additionally known as monozygotic twins. They result from the treatment of a…
Q: Which of the following are epigenetic marks?a. Methylated basic amino acids in histone tailsb.…
A: Any changes in the DNA or its related components which effectively alter the gene expression, tunes…
Q: Which of the following processes is an example of an epigenetic effect (meaning not originating in…
A: Genes are very much crucial in regulating the health of the body and behavior of an individual which…
Q: many more mRNA transcripts than there are genes. Why isn’t the number the same?
A: Regulatory protein (or gene-regulatory protein) is any protein that controls the transcription.…
Q: Which are possible methods of epigenetics? (Select all that apply) O histone modification by…
A: Epigenetics It is defined as the study of heritable changes in expression of genes which do not…
Q: . Null alleles (mutant genes) produce no protein product. This is a genetic change. However,…
A: Introduction Epigenetics is the study of how your behaviour and environment can influence how your…
Q: There are several different types of genes within a genome that serve specific functions within the…
A: A genome is an organism's full set of genetic information. It contains all of the information that…
Q: Define Epigenetic Inheritance Epigenetic inheritance Multiple Choice includes a subset of epigenetic…
A: The environmental conditions and factors influence the working of genes, these conditions can change…
Q: To cause cancer, proto-genes require blank allele(s) to be mutated and therefore are considered…
A: ANSWER;- To cause cancer, proto-genes require a single allele(s) to be mutated and therefore are…
Q: Why are some genes expressed and some not?
A: Gene expression is dependent on many factors Genotype of the individual Environmental Status Gene…
Q: Explain DNA methylation. How does this process influence cellular function?
A: DNA methylation is a process in which Dna bases are Methylated with the help of enzyme Methyl…
Q: an adult with a history of tanning has his genome sequenced. The beginning of a protein coding…
A: Mutations are the changes in the genetic sequence that may result in genotypic or phenotypic…
Q: How does epigenetic regulation differ from other forms of gene regulation? O It is easily…
A: Unlike genetic changes, epigenetic changes are reversible and do not change your DNA sequence, but…
Q: Chromatin remodeling is linked to epigenetics. Explain how this works and indicate the driving…
A: Epigenetics is referred to as the study of phenotype changes that are inheritable and does not…
Q: what are the normal funtions of the p53 gene
A: p53 gene is also called as tumour suppressor gene or Tp53 gene produces the protein called tumour…
Q: Describe how epigenetic changes underlie paramutation.
A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…
Q: s the process to multiply the number of a target ge
A: The target DNA sequence is a particular sequence made up primarily of the nucleotides adenine,…
Q: Describe how a mutation in the regions below could cause such a drastic effect that it creates a…
A: The transcription is the production of RNA from the DNA and the translation is the production of…
Q: Define the epigenetic mechanisms - chromatin remodeling bythe addition or removal of chemical groups…
A: Introduction Expression of gene is highly under control by various mechanisms such as histone…
Q: Explain DNA methylation. How does this process influence cellular function?
A: DNA methylation is a biological process. It is an aging process and lifestyle factor such as smoking…
Q: Epigenetic changes in gene regulation are caused by _ _ _ _ _ _ _ a. missing nucleotides or…
A: Epigenetics refers to both heritable and non heritable changes in gene expression that are not…
does P53 It integrate together information from over a hundred proteins about the mutational state of the genome
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- As the most junior member of a lab, you are tasked with generating cell lines that accumulate DNA damage to investigate how random mutations affect transformation of cells into cancer cells. You decide to mutate proteins in the p53 pathway. Which three proteins would you mutate? Explain your reasoning.Can you think of two ways in which the function of p53 can be disrupted?Why is the p53 R273W mutation preventing p53 from binding to DNA?
- "Changes to the p53 protein structure can be caused by differences in DNA and can affect protein function." Can you give detailed explanation why this is causation and not correlation? The explanation should be related with mutation, structure changes during protein synthesis, chemical property changes in amino acids, and functions of p53 protein.what are the normal funtions of the p53 geneWhat percentage of the human genome is nowpredicted to have functionality in at least one cell type?
- If you were to design an experiment to get p53 back into cancer cells, how would you go about that work? How would you direct p53 into the nucleus of cancer cells without directing it to the nucleus of healthy cells? As an overabundance of p53 in healthy cells would cause problems. Could someone in depth answer these questions for me and explain them cellularly.In a few sentences, describe how p53 guards the genome. Include at least two specific ways that p53 guards the genome. In a few more sentences, describe the structure and function of the p53 protein. Structure: what domains are present in the p53 protein? Do p53 work as a single protein or as part of a complex? Function: what do the different domains do? How can p53 do so many different things?DO NOT COPY IN GOOGLE OR IN BARTLEBY QUESTION: - Why is TP53 called the Guardian of the genome?
- : The effects of DNA mutations within the p53 gene on the structure and function of the protein encoded by the gene. The essay should focus on the following discussion points: The normal functions of the p53 gene. Known mutations of the gene. The impact of mutations on the structure of the protein encoded by the gene. The impact of mutations on the function of the protein. Current therapeutic interventions that aim to address the impact of mutations on gene functionDescribe the nature of p53 reactivation as acancer-fighting strategyhttps://ny.pbslearningmedia.org/resource/biot09.sci.life.gen.epigenetics/epigenetics/ Explain DNA methylation. How does this process influence cellular function?