During nucleic acid hybridization, the probe is labelled    for DNA stability   to increase probe-test DNA binding    to identify the location of probe and the test DNA binding   for amplification

Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Chapter19: Genomes And Proteomes
Section: Chapter Questions
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9.

During nucleic acid hybridization, the probe is labelled 

 

for DNA stability

 

to increase probe-test DNA binding 

 

to identify the location of probe and the test DNA binding

 

for amplification

11.

What is not true for Sequence tagged site (STS) markers:

 
 

cannot be mapped by fluorescence in situ hybridization (FISH)

 

subset of STS markers are known as expressed sequence tag (EST) markers

 

can readily be screened by a PCR assay

 

short DNA sequences that occur at a unique location in the genome

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