Explain in your own words why the terms "dominant" and "recessive" in terms of genetic inheritance are context dependant. Typically, the terms dominant and recessive refer to the phenotype and not to alleles. In your answer, also explain why this is the case.
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Q: cessive because the trait skips a gene
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- Let’s suppose a gene exists as a functional wild-type allele and anonfunctional mutant allele. At the organism level (i.e., at the levelof visible traits), the wild-type allele is dominant. In a heterozygote,discuss whether dominance occurs at the cellular or molecularlevel. Discuss examples in which the issue of dominance dependson the level of examination.Single gene Mendelian inheritance patterns: if you are told the phenotype of the parents and whether the trait is dominant or recessive etc, be able to predict the genotype of the children. If you are told the phenotype of the parent as well as the inheritance pattern, be able to predict the parent’s genotype. Be able to set up and use a Punnett square to solve problems and make predictions. Be able to explain the major steps in how information from our genes is used to make proteins. Or to show it in a labeled diagram. Be able to explain whatis transcription, translation. Where in the cell do these processes occur? In what order? What type of molecules are being made [DNA, RNA, protein]? What are their building blocks? What is a mutation? How can a mutation in DNA cause a change in a protein? (use the following terms to answer: codon, transcription, translation, mRNA). What is gene expression? Why is regulation of gene expression important for normal…Describe why there is a fundamental difference between the expression of a trait that is determined by polygenes and the expression of a trait that is determined monogenetically.
- Height in humans is controlled by the additive action of genes and the action of environmental factors. For the purposes of this problem, assume that height is controlled by four genesA, B, C, and Dand that there are no environmental effects. Assume further that additive alleles contribute two units of height and partially additive alleles contribute one unit of height. a. Given these assumptions, can two individuals of moderate height produce offspring that are much taller and shorter than either parent? If so, how can this happen? b. Can someone of minimum height and someone of intermediate height have children taller than the parent of intermediate height? Why or why not?Clubfoot is a common congenital birth defect. This defect is caused by a number of genes but appears to be phenotypically distributed in a noncontinuous fashion. Geneticists use the threshold model to explain the occurrence of this defect. Explain this model. Explain predisposition to the defect in an individual who has a genotypic liability above the threshold versus an individual who has a liability below the threshold.INTERPRET DATA Using the graph in Figure 11-20, determine how many offspring were involved in the hypothetical cross studying skin color. What percentage had the lightest skin possible? the darkest skin possible? Figure 11-20 Polygenic inheritance in human s pigmentation This simplified example assumes that skin pigmentation in humans is governed by alleles of three unlinked loci. The alleles producing dark skin (A, B, and C) are represented by capital letters, but they are not dominant. Instead, their effects are additive. The number of dark dots, each signifying an allele producing dark skin, is counted to determine the phenotype. A wide range of phenotypes is possible when individuals of intermediate phenotype mate and have offspring (AaBbCc AaBbCc). The expected distribution of phenotypes is consistent with the superimposed normal distribution curve.
- The ABO blood groups in humans are expressed as the IA,IB and i alleles. The IAallele encodes the A blood group antigen, IB encodes B, and i encodes O. Both A and B are dominant to 0. If a heterozygous blood type A parent (IAi) and a heterozygous blood type B parent (IBi) mate, one quarter of their offspring are expected to have the AB blood type IAIBin which both arnigens are expressed equally. Therefore, ABO blood groups are an example of: a. multiple alleles and incomplete dominance b. codominance and incomplete dominance c. incomplete dominance only d. multiple alleles and codominanceConnection to Quantitative traits: SNPs are inherited in a Mendelian fashion and are often polygenic in nature. We can think of SNPs in terms of either contributing or non-contributing alleles. A study of SNPs correlated with heart disease has shown that heart problems are severe if 9 or more of the alleles at 6 loci are of the contributing variety. What is the probability the following parents will have a child that is susceptible heart disease? AaBbccDDEEFf x AaBbCCDdEeffApplying Hardy-Weinberg equilibrium. For instance, a trait is caused by the homozygous state of a gene that is recessive and autosomal. 9% of individuals are expressing the phenotype. What is the percentage of individuals that are heterozygous?
- In a species of plant, two genes control flower color. The red allele(R) is dominant to the white allele (r); the color-producing allele(C) is dominant to the non-color-producing allele (c). You suspectthat either an rr homozygote or a cc homozygote will producewhite flowers. In other words, rr is epistatic to C, and cc is epistatic to R. To test your hypothesis, you allow heterozygous plants(RrCc) to self-fertilize and count the offspring. You obtain the following data: 201 plants with red flowers and 144 with white flowers. Conduct a chi square analysis to see if your observed data areconsistent with your hypothesis.Eye Color is a trait that involves a number of genes. To simplify our example, we can break down the traitinto two phenotypes: dark color and light color eyes. Dark coloration is considered dominant, or isexpressed in a heterozygous condition (when the alleles are different).Q: If you have one light eyed parent and one parent that is homozygous for dark eye color, what are thepotential eye colors of their offspring (young)? To start, what do the Parents’ alleles look like? What istheir Genotype? (Remember, you pick which letter you want to use)Light eye colored parent:Dark eye colored parent:One of the things Mendel designed was a way to provide information about how the genes are passed onfrom parent to offspring. He designed something called a Punnett Square. This square places the parents’alleles outside the box, then uses those alleles to fill in the squares.Let’s start with a reminder of what we know about the parents: Parent Phenotype(appearance) Genotype(alleles) 1 2Assume that hair color, hair line, and skin tone in humans are different traits that are controlled by independently-assorting genes. Brown hair (B) is dominant to blond hair (b), a widow’s peak (W) is dominant to a straight hairline (w), and freckles (F) are dominant to no freckles (f). What is the likelihood that the child of a BBWwff person and a bbwwFF person will have: brown hair, a widow’s peak, and freckles? There is no missing information, just have to set up the punet square and I'm not sure how to do all traits.