fill in the blank When the cell goes from M to GI, the number of nucleosomes on this stretch of DNA should ------, and the width of the chromatin fiber should -------.
Q: Give at least one example of a chromosomal structureor function affected by the following mechanisms…
A: Chromosomes are thread-like structure of nucleic acids and protein, which are found in the nucleus…
Q: Malaria, one of the most pervasive and destructive of all infectious diseases, is caused by…
A: Gene regulation includes chemical and structural changes in genetic material, or mechanism which…
Q: Discuss the differences between the compaction levels of metaphase chromosomes and those of…
A: During interphase, chromosomes are arranged in a less condensed or compact manner. They occupy the…
Q: : Nuclear changes in morphology of reversible cell injury: Nuclear Nuclear changes in morphology of…
A: Introduction The death of body tissue is known as necrosis. It happens when there isn't enough…
Q: When chromatin is in the form of a 30 nm fibril, how many copies of H1 and H2A histone proteins…
A: The DNA is wrapped around the nucleosome within the cell to form chromatin. Nucleosome – it is a…
Q: Which of the following statements correctly describes the structure of chromatin around the promoter…
A: Chromatin is a complex of DNA and protein found in eukaryotic cells.
Q: Typically, increased acetylation and decreased methylation of histone N-terminal tails in…
A: Histone acetylation and deacetylation are the processes by which the lysine deposits inside the…
Q: Which type of chromatin makes dark bands? Does this type usually contain more or less active genes?…
A: The human genome contains more than 3 billion nucleotides(organic molecules consist of nucleoside…
Q: Which of the following statements are correct? Explain your answers. Centrosomes are replicated…
A: Since we only answer up to 3 sub-parts, we’ll answer the first 3. Please resubmit the question and…
Q: Consult Figure 2. Would you consider this figure to be depicting euchromatin, or heterochromatin,…
A: Chromatin exists as euchromatin or heterochromatin. Euchromatin are loosely bound,less condensed,…
Q: The gel below is the result of a Sanger sequencing run of part of Exon 3 of the Mstn gene, which…
A: In Sanger sequencing, the objective is to analyze the sequence of a given strand of DNA. To obtain…
Q: cell is homozygous for a LOF mutation in the histone acetyltransferase (HAT) gene. Which of the…
A: HAT stands for Histone acetyl transferase. The LOF refers to the loss of function mutation. If a…
Q: Draw and describe the “beads on a string” structure of the chromatin. 4. What are the proteins found…
A: The haploid human genome contains approximately three billion base pairs of DNA. Each base pair is…
Q: Below you will find the normal p53 gene found on chromosome 17 and a mutated version of the gene.…
A: To solve such questions, we should know the corresponding complementarity between the bases and that…
Q: Models of higher-order compaction suggest that thenucleosomal fiber is supercoiled into a shorter…
A: The primary role of nucleus as a DNA storage and replication site requires the compaction and…
Q: Which structure in the eukaryotic chromosome is about 11 nm in diameter, contains 8 histone proteins…
A: In eukaryotes, all of the cell's chromosomes are stored inside a structure called the nucleus. Each…
Q: Disdis -how do RB and p53 negatively regulate the cell cycle in G1? describe the events that occur…
A: A series of events which takes place in a cell due to which it divides and forms two daughter cells…
Q: Describe the levels of chromatin packing you’d expect to see in aninterphase nucleus.
A: DNA is Deoxyribonucleic acid has a deoxyribose as pentose sugar. Its structure has H group attached…
Q: Would you expect to find active genes in regions of heterochromatin or euchromatin
A: DNA is the genetic material of all organisms except some viruses. The DNA are double stranded…
Q: UESTION 4 human cell contains 46 chromosomes, which are often "decondensed," and the nucleus is 5-10…
A: Nucleus is a central part of Eukaryotic cell which is very important as it contains chromosomes that…
Q: Fluorescent beta-tubulin is microinjected into the cytoplasm of a mammalian cell in interphase.…
A: Introduction Tubulin can refer to either the tubulin protein superfamily of globular proteins or one…
Q: Let’s suppose you have isolated chromatin from some bizarreeukaryote with a linker region that is…
A: Introduction Each human cell contains around 3 metres of DNA which contains about 3 Billion base…
Q: 2. Give at least one example of a chromosomal structureor function affected by the following…
A: Chromosomes are the thread-like structures that possess a tightly coiled DNA molecule around the…
Q: The nuclear matrix composition: a. lamina, nucleosome b. cortex, lamina, c. nucleosome d. lamina,…
A: The nuclear matrix is described as a type of structure that majorly comprises non-histone proteins.…
Q: You are interested in studying a gene called pumper that is important for heart function. The pumper…
A: Chromatin is the region containing gene. Some genes are in open state and some genes are in closed…
Q: Chromatin is differentiated into heterochromatin and euchromatin regions, on the basis of staining…
A: Answer: Introduction: Some proteins are dense chromosomal DNA into the microscopic gap of the…
Q: structure of DNA from the level of a gene to a condensed mitotic chromosome. At each of the four…
A: Gene expression is the process in which transcription is followed by translation. In transcription…
Q: Which one of the following statements about nucleosomes is false? a) The DNA double helix wraps…
A: Introduction Nucleosomes are eukaryotic chromatin's basic repeating structural units, comprised of…
Q: The physical constraints to DNA replication presented by the chemical structure of DNA include…
A: Acetylation of chromatin is correct statement . As acetylation removes the positive charge on the…
Q: An old genetic observation is that a normally active gene will be silenced if it is moved by…
A: Histone alterations are linked to different transcription stages and functions, and epigenetic…
Q: Rather surprisingly, some cellular components that we know best from our study of nuclear protein…
A: Nuclear protein import is a selective process where all nuclear proteins are cytoplasm-synthesized…
Q: What structure of the nucleus has the function of transporting small molecules through the nuclear…
A: The nucleus is an important membrane-bound organelle in a eukaryotic cell that houses the genetic…
Q: Which of the following is the most compact level of chromatin structure? Metaphase chromosomes…
A: Metaphase chromosomes is the most compact level of chromatin structure.
Q: 6) There is clear evidence that chromatin state is directly related to the ability of proteins to…
A: The chromosomes appear as a mass of greatly fine tangled string called "chromatin." Chromatin is…
Q: In eukaryotic cells, the DNA is tightly packed in the form of chromatin. His- tones are positively…
A: Hello. Since your question has multiple parts, we will solve the first question for you. If you want…
Q: Which of the following represents the order of increasingly higher levels of organization of…
A: Histones octamer play a key role in the packaging of DNA. DNA wraps the core histones and forms the…
Q: asic amino acids including lysine. DNA and histones collectively form chromatin. Open open and…
A: Histones can be defined as the family of basic proteins that are associated with the DNA in the…
Q: Which of the following statements concerning eukaryotic chromatin is true. Histones have an…
A: Eukaryotic chromatin is made up of protein and DNA . It consists of beads referred to as nucleosome.…
Q: Which region of chromatin is transcriptionally silent?a) Nucleoidb) Centromerec) Euchromatind)…
A: Deoxyribonucleic acid (DNA) is a molecule composed of two polynucleotide chains. It coils around…
Q: Suppose a geneticist introduced a small interfering RNA (siRNA) that was complementary to the FLC…
A: The regulation of gene expression is done by the pre-mRNA processing and degradation of m-RNA. The…
Q: Describe chromatin when CpG islands are unmethylated?
A: CpG islands have the GC (guanine-cytosine) content greater than 50% that indicates the mutating…
Q: One histone modification that is seen consistently inmany species is the addition of an acetyl group…
A: Introduction: Histone is a type of protein that functions to support the chromosome structure.…
Q: Genes are not always active in cells. The cell has evolved to edit its chromatin state in accord…
A: Chromatin is the region placed within DNA that contains DNA and proteins like histones. Chromatin…
Q: dentify TWO major categories of chromatin responsible in compaction of chromosome
A: Chromatin : It is a complex of DNA and protein which forms chromosomes within the nucleus of the…
Q: Look at the two yeast colonies in Figure Q4–3. Eachof these colonies contains about 100,000 cells…
A: The expression of genes is regulated at several levels. It includes both genetic and epigenetic…
Q: Which of the following statements about the function of the centrosome is FALSE? Microtubules…
A: Centrosomes are organelles that serve as the main microtubule-organizing centers for animal cells.…
Q: Define constitutive heterochromatin
A: Chromosomes are thread or string-like structures situated inside the nucleus of creature and plant…
Q: Which structure in the eukaryotic chromosome is about 2 nm in diameter, contains no histone proteins…
A: Transcription is the cycle by which the data in a strand of DNA is duplicated into another molecule…
please fill in the blank
When the cell goes from M to GI, the number of nucleosomes on this stretch of DNA should ------, and the width of the chromatin fiber should -------.
Please select one
Newly made lamins should ( single peptide = SP), or (nuclear localization = NLS) or (Transit peptide =TP) or ( Transmembrane domain) or ( SP and NLS) or ( SP or TP) or (transcription activating domain) or ( None of these)
Step by step
Solved in 2 steps
- Let’s suppose you have isolated chromatin from some bizarreeukaryote with a linker region that is usually 300–350 bp inlength. The nucleosome structure is the same as in other eukaryotes.If you digested this eukaryotic organism’s chromatin with ahigh concentration of DNase I, what would be your expectedresults?An article entitled “Nucleosome Positioning at the Replication Fork” states: “both the ‘old’ randomly segregated nucleosomes as well as the ‘new’ assembled histone octamers rapidly position themselves (within seconds) on the newly replicated DNA strands” [Lucchini et al. (2002)]. Given this statement, how would one compare the distribution of nucleosomes and DNA in newly replicated chromatin? How could one experimentally test the distribution of nucleosomes on newly replicated chromosomes?Look at the two yeast colonies in Figure Q4–3. Eachof these colonies contains about 100,000 cells descendedfrom a single yeast cell, originally somewhere in the mid-dle of the clump. A white colony arises when the Ade2 geneis expressed from its normal chromosomal location. Whenthe Ade2 gene is moved to a location near a telomere, itis packed into heterochromatin and inactivated in mostcells, giving rise to colonies that are mostly red. In theselargely red colonies, white sectors fan out from the middleof the colony. In both the red and white sectors, the Ade2 gene is still located near telomeres. Explain why white sec-tors have formed near the rim of the red colony. Based onthe patterns observed, what can you conclude about thepropagation of the transcriptional state of the Ade2 genefrom mother to daughter cells in this experiment?
- what are we looking at in part (b)? Is this an11-nm fiber, a 30-nm fiber, or a 300-nm fiber? Does this DNAcome from a cell during M phase or interphase?Arrange the levels of chromatin packing from most "open" to most condensed (chromosome, loops, nucleosomes, heterochromatin, 30-nm chromatin fiber)A part of a sequenced chromosome has the sequence (on one strand)ATTGCATCCGCGCGTGCGCGCGCGATCCCGTTACTTTCCG. Which part of thissequence is most likely to take up the Z conformation?
- Eukaryotic life also uses chromatin modifications to turn transcripts on and off. We talked about PARP-1 and its ability to remodel chromatin in response to what?Which of the following statements most accurately represent chromatin state and transcription? Group of answer choices 1.Histone deacetylases promote closed chromatin and result in repressed transcription 2.Open chromatin is associated with hypoacetylation and has high levels of transcription 3.Histone acetyltransferases result in hypoacetylation and high levels of transcription 4.Hyperacetylation is associated with closed chromatin and low levels of transcriptionGive at least one example of a chromosomal structureor function affected by the following mechanisms formodulating chromatin structure:a. Posttranslational changes of the normal histonesfound in the nucleosome
- . For each of the terms in the left column, choose thebest matching phrase in the rigf. satellite DNA 6. small basic proteins that bind toDNA and form the core of thenucleosomeg. chromatin 7. complex of DNA and proteinswhere spindle fibers attach to achromosomeh. cohesin 8. beadlike structure consisting ofDNA wound around histoneproteinsi. histones 9. protein complex that protectstelomeres from degradation andend-to-end fusionsj. shelterin 10. regions of a chromosome thatare distinguished by stainingdifferencesht column.a. telomere 1. protein complex that keepssister chromatids togetheruntil anaphaseb. G bands 2. origin of replication in yeastc. kinetochore 3. repetitive DNA found near thecentromere in higher eukaryotesd. nucleosome 4. specialized structure at the endof a linear chromosomee. ARS 5. complexes of DNA, protein, andRNA in the eukaryotic nucleusChromatin is differentiated into heterochromatin and euchromatin regions, on the basis of staining behaviour in a typical nucleus. Which of the given statements is/are correct w.r.t. heterochromatin? (A) Lightly stained region (B) Chromatin is densely packed (C) Transcriptionally it is inactive (D) Darkly stained region 1. (A) only 2. (A) and (C) only 3. (A), (B) and (C) 4. (B), (C) and (D)Heterochromatin consists of a) region of euchromatin devoid of histones. b) an AT-rich region occurs every 200 base pairs. c) decondensed, transcriptionally active chromatin. d) highly condensed, transcriptionally inactive chromatin