One histone modification that is seen consistently inmany species is the addition of an acetyl group to thetwelfth lysine in the H4 protein. If you were a geneticist working on yeast and had a clone of the H4 gene,what could you do to test whether the acetylation atthis specific lysine was necessary for the functioningof chromatin?

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter29: Transcription And The Regulation Of Gene Expression
Section: Chapter Questions
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One histone modification that is seen consistently in
many species is the addition of an acetyl group to the
twelfth lysine in the H4 protein. If you were a geneticist working on yeast and had a clone of the H4 gene,
what could you do to test whether the acetylation at
this specific lysine was necessary for the functioning
of chromatin?

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