Histones contain many basic amino acids including lysine. DNA and histones collectively form chromatin. Openchromatin is much more open and accessible to the transcriptional machinery than closed chromatin. Histonelysine acetylation is associated with open chromatin and occurs near genes that are being actively transcribed.Part A Given what you know about the chemical properties of DNA and the function of histones. whv dohistones contain so many basic amino acids? Answer in no more than two sentences.Part B Given what you know about how acetylation affects lysine, why does histone lysine acetylation openchromatin? Answer in one sentence only.

Histones can be defined as the family of basic proteins that are associated with the DNA in the…

asic amino acids including lysine. DNA and histones collectively form chromatin. Open open and accessible to the transcriptional machinery than closed chromatin. Histone ciated with open chromatin and occurs near genes that are being actively transcribed. you know about the chemical properties of DNA and the function of histones. whv do tain so many basic amino acids? Answer in no more than two sentences. you know about how acetylation affects lysine, why does histone lysine acetylation oper Answer in one sentence only.

asic amino acids including lysine. DNA and histones collectively form chromatin. Open open and accessible to the transcriptional machinery than closed chromatin. Histone ciated with open chromatin and occurs near genes that are being actively transcribed. you know about the chemical properties of DNA and the function of histones. whv do tain so many basic amino acids? Answer in no more than two sentences. you know about how acetylation affects lysine, why does histone lysine acetylation oper Answer in one sentence only.

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter8: The Structure, Replication, And Chromosomal Organization Of Dna

Section: Chapter Questions

Problem 25QP: Discuss the levels of chromosomal organization with reference to the following terms: a. nucleotide...

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Similar questions

Which one of the following statements about nucleosomes is false? a) The DNA double helix wraps around the nucleosome. b) The sequence of amino acid in a histone tail is altered during chromatin remodeling. c) A nucleosome is composed of 8 histone proteins; two copies of each type of histone. d) A large percent of the nucleosome is positively charged.
Heterochromatin and Euchromatin Have Which Different Histone modifications
Which of the following is likely to be transcriptionally expressed? euchromatin and DNA with methyl groups euchromatin DNA with methyl groups DNA with acetylated histones euchromatin and DNA with acetylated histones
Which of these is NOT true of nucleosomes? A. Some post-translational modifications to histone proteins serve as binding sites for transcription factors. B. The position of nucleosomes is fixed on the genome and can not be changed. C. The position and post-translational modifications of histones can be inherited through mitosis. D. The binding between DNA and histone proteins can be disrupted by post-translational modifications.
A cell is homozygous for a LOF mutation in the histone acetyltransferase (HAT) gene. Which of the following is/are true? a. Chromatin in the cell will be more condensed than usual, decreasing expression of genes that should be expressed. b. This will lead to histones with more positive charges on their tails, increasing the interaction between histones and the DNA backbone. c. This will lead to a decrease in DNA methylation and therefore cause an increase in gene expression. d. Chromatin in the cell will be less condensed than usual, increasing expression of genes that should not be expressed.
Describe the mechanism by which histone modifications are established after DNA replication and cell division. What are some things that could go wrong if modifications can't be maintained? Think about what histone modifications do to DNA and why cells maintain parts of their chromosome as heterochromatin.
Which of the following statements most accurately represent chromatin state and transcription? Group of answer choices 1.Histone deacetylases promote closed chromatin and result in repressed transcription 2.Open chromatin is associated with hypoacetylation and has high levels of transcription 3.Histone acetyltransferases result in hypoacetylation and high levels of transcription 4.Hyperacetylation is associated with closed chromatin and low levels of transcription
Heterochromatin consists of a) region of euchromatin devoid of histones. b) an AT-rich region occurs every 200 base pairs. c) decondensed, transcriptionally active chromatin. d) highly condensed, transcriptionally inactive chromatin
Cell (A) contains 3.1 billion (3.1 x 109) base pairs of DNA. Each nucleosome has about 200 bp of DNAwrapped around the histone core.a. What is the maximum number of nucleosomes that can be present in the cell?b. What is the maximum number of H2A histone protein molecules that can be present in the cell?
Give at least one example of a chromosomal structureor function affected by the following mechanisms formodulating chromatin structure:a. Posttranslational changes of the normal histonesfound in the nucleosome
Many proteins other than histones are found associated with chromosomes. What roles do these nonhistone proteins play? Why do chromosomes have moredifferent types of nonhistone than histone proteins?
The diagram below shows the structure of DNA from the level of a gene to a condensed mitotic chromosome. At each of the four locations marked, indicate how a gene may be regulated by selecting from the choices given. Some answer choices may fit into more than one position; however, you should use each answer choice only once. Choices given: Alternative splicing within the gene sequence can lead to different forms of mRNA. A promoter region can be blocked by another protein. Histone deacetylation can prevent DNA from unwinding. A regulatory region can be bound and increase transcription rates.