For a locus with two alleles (B and b) in a population at risk from an infectious neurodegenerative disease, 16 individuals have the genotype BB, 92 individuals have Bb and 12 individuals have bb. Use the Hardy-Weinberg equation to determine whether this population appears to be evolving
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For a locus with two alleles (B and b) in a population at risk
from an infectious neurodegenerative disease, 16 individuals
have the genotype BB, 92 individuals have Bb and 12
individuals have bb. Use the Hardy-Weinberg equation to
determine whether this population appears to be evolving.
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- If 80% of a population has a heterozygous phenotype, and 16% of that population shows arecessive phenotype, is that population in Hardy-Weinberg equilibrium? In other words, doesthe population obey the rules of H-W? Perform a statistical analysis to determine your finalanswer.Suppose the frequency of the recessive allele a for the recessive condition albinism is 0.2 Assume the Hardy-Weinberg distribution. What is the frequency of albinism in the general population? What fraction of the population are carriers?In a certain population of frogs, 120 are green, 60 arebrownish green, and 20 are brown. The allele forbrown is denoted GB, while that for green is GG, andthese two alleles are incompletely dominant.a. What are the genotype frequencies in thepopulation?b. What are the allele frequencies of GBand GG inthis population?c. What are the expected frequencies of the genotypes if the population is at Hardy-Weinbergequilibrium?
- In a given population, 1 out of 400 individuals has cancer caused by a recessive allele g. Assuming the population is in Hardy-Weinberg equilibrium, what is the expected proportion of individuals who are carriers?The frequency of individuals who express a recessive disease in a population is 16%. What variable in the Hardy Weinberg equations does the 16% refer to? Why?The human MN blood group is determined by two codominant alleles, M and N. The following data were obtained from five human populations: A. Calculate the allele frequencies in these five populations. B. Which populations appear to be in Hardy-Weinberg equilibrium? C. Which populations do you think have experienced significant intermixing due to migration?
- Sickle-cell anemia is a recessive disease that afflicts approximately 1 in 12 African Americans, meaning that the frequency of ss homozygotes is 0.09. Assuming the African American population is in Hardy-Weinberg equilibrium, what is the frequency of Ss carriers in this population?In monkeys, black coat color (B) is dominant over brown color (b). A population of monkeys was found to be composed of 67 brown coated individuals and 119 black coated individuals. Based upon the Hardy‑Weinberg formula, what proportion of the population is expected to have the genotype BB? Based upon the Hardy‑Weinberg formula, what proportion of the population is expected to bave black coat color?Consider the B locus which has two alleles in a population: B and b. Researchers examined the genotypes several individuals for this locus and obtained the following numbers B/B: 302individuals B/b: 56individuals b/b: 17individuals If the B locus is at Hardy-Weinberg equilibrium, what would the expected number of individuals with the Bb genotype? Round your answer to the closest full number.
- A gene has two alleles A (frequency = p) and a(frequency = q). If a population is at Hardy-Weinbergequilibrium, develop mathematical expressions interms of p and q that predict the following matingfrequencies:a. Between two AA homozygotesb. Between two aa homozygotesc. Between two Aa heterozygotesd. Between an AA homozygote and an aa homozygotee. Between an AA homozyote and an Aa heterozygotef. Between an aa homozygote and an Aa heterozygote Considering your answers to parts (a)–(f):g. Do the six possibilities listed account for all possible matings? How would you know whether this istrue mathematically? Demonstrate this latter pointby setting p equal to an arbitrary number between0 and 1 such as 0.2.h. Can you develop a simple, general rule for calculating the mating frequencies between individualsof the same genotype versus the mating frequencies between individuals of different genotypes?i. If the population is equally divided between malesand females, what proportion of all matings…In a population that meets the Hardy–Weinberg equilibrium assumptions, 81% of the individuals are homozygous for a recessive allele. What percentage of the individuals would be expected to be heterozygous for this locus in the next generation?If the frequency of a dominant allele “B” in a population is 80%, and assuming genetic equilibrium in this population, what percentage of the offspring in the next generation could be expected to have the heterozygous genotype?